Confirmatory molecular method for HTLV‐1/2 infection in high‐risk pregnant women

Confirmatory molecular method for HTLV‐1/2 infection in high‐risk pregnant women INTRODUCTIONHuman T‐lymphotropic virus‐1 (HTLV‐1) is an oncogenic human retrovirus that causes adult T‐cell leukemia/lymphoma (ATLL) and progressive HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP). HTLV‐2, which is known to be endemic in African Pygmies and Native Americans as well as common in drug users, has not been clearly linked to any diseases.Worldwide, it is estimated that about 15 to 20 million people are infected with HTLV. The prevalence varies according to the geographic area, socio‐demographics and ethnic composition of the population, as well as specific risk groups, such as injecting drug users, sex workers, and people living with HIV (PLWH). In Brazil, it is estimated that 2.5 million people are infected with HTLV, with a frequency that varies according to geographic localization, but Brazil is undoubtedly considered an endemic area. The virus is transmitted from human to human through infected lymphocytes and may be acquired through sexual intercourse, blood transfusions, organ transplantations, contaminated needle reuse, and from mother‐to‐child transmission (MTCT) during pregnancy, at birth, and, more commonly, through breastfeeding.The studies evaluating the frequency of HTLV‐1 infection among pregnant women in Brazil have shown prevalence levels varying from 0.08% to 1.30%. However, investigation of HTLV during prenatal care is scarce, and little http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Medical Virology Wiley

Loading next page...
 
/lp/wiley/confirmatory-molecular-method-for-htlv-1-2-infection-in-high-risk-PTRcIOy0Tg
Publisher
Wiley
Copyright
© 2018 Wiley Periodicals, Inc.
ISSN
0146-6615
eISSN
1096-9071
D.O.I.
10.1002/jmv.25014
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTIONHuman T‐lymphotropic virus‐1 (HTLV‐1) is an oncogenic human retrovirus that causes adult T‐cell leukemia/lymphoma (ATLL) and progressive HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP). HTLV‐2, which is known to be endemic in African Pygmies and Native Americans as well as common in drug users, has not been clearly linked to any diseases.Worldwide, it is estimated that about 15 to 20 million people are infected with HTLV. The prevalence varies according to the geographic area, socio‐demographics and ethnic composition of the population, as well as specific risk groups, such as injecting drug users, sex workers, and people living with HIV (PLWH). In Brazil, it is estimated that 2.5 million people are infected with HTLV, with a frequency that varies according to geographic localization, but Brazil is undoubtedly considered an endemic area. The virus is transmitted from human to human through infected lymphocytes and may be acquired through sexual intercourse, blood transfusions, organ transplantations, contaminated needle reuse, and from mother‐to‐child transmission (MTCT) during pregnancy, at birth, and, more commonly, through breastfeeding.The studies evaluating the frequency of HTLV‐1 infection among pregnant women in Brazil have shown prevalence levels varying from 0.08% to 1.30%. However, investigation of HTLV during prenatal care is scarce, and little

Journal

Journal of Medical VirologyWiley

Published: Jan 1, 2018

Keywords: ; ; ;

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off