Comparison of long‐term mortality according to obesity in patients with successful percutaneous chronic total occlusion interventions using drug‐eluting stents

Comparison of long‐term mortality according to obesity in patients with successful percutaneous... INTRODUCTIONPercutaneous coronary intervention (PCI) for chronic total occlusion (CTO) lesions is one of the most complex percutaneous procedures. Previous studies have suggested that considerable clinical benefits could be achievable after the successful revascularization of CTO lesions . In particular, improved survival has been reported after the successful PCI of CTO . Recently, more attempts to use PCI for CTO lesions have been made because of advanced devices and cumulative operator clinical experience in clinical practice .In the general population, obesity increases the risk of numerous comorbidities and cardiovascular (CV) disease . Furthermore, a high body mass index (BMI) is strongly associated with increased mortality . However, the phenomenon known as the “obesity paradox” has been replicated in patients with established coronary artery disease (CAD), especially in the era of PCI . Considering the potential impact of both successful reperfusion and the different methods used on the prognosis in CAD patients treated with PCI, major limitations to explaining the phenomenon of the obesity paradox might be present. Furthermore, these studies examined inconsistently severe coronary lesions, although the obesity paradox could be influenced by the lesion characteristics in the era of PCI . Thus, there is a paucity of data on http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Catheterization and Cardiovascular Interventions Wiley

Comparison of long‐term mortality according to obesity in patients with successful percutaneous chronic total occlusion interventions using drug‐eluting stents

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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 Wiley Periodicals, Inc.
ISSN
1522-1946
eISSN
1522-726X
D.O.I.
10.1002/ccd.27110
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTIONPercutaneous coronary intervention (PCI) for chronic total occlusion (CTO) lesions is one of the most complex percutaneous procedures. Previous studies have suggested that considerable clinical benefits could be achievable after the successful revascularization of CTO lesions . In particular, improved survival has been reported after the successful PCI of CTO . Recently, more attempts to use PCI for CTO lesions have been made because of advanced devices and cumulative operator clinical experience in clinical practice .In the general population, obesity increases the risk of numerous comorbidities and cardiovascular (CV) disease . Furthermore, a high body mass index (BMI) is strongly associated with increased mortality . However, the phenomenon known as the “obesity paradox” has been replicated in patients with established coronary artery disease (CAD), especially in the era of PCI . Considering the potential impact of both successful reperfusion and the different methods used on the prognosis in CAD patients treated with PCI, major limitations to explaining the phenomenon of the obesity paradox might be present. Furthermore, these studies examined inconsistently severe coronary lesions, although the obesity paradox could be influenced by the lesion characteristics in the era of PCI . Thus, there is a paucity of data on

Journal

Catheterization and Cardiovascular InterventionsWiley

Published: Jan 1, 2018

Keywords: ; ; ;

References

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