Comparison of common risk stratification indices to predict outcomes among stage IV cancer patients with bowel obstruction undergoing surgery

Comparison of common risk stratification indices to predict outcomes among stage IV cancer... INTRODUCTIONMalignant bowel obstruction is common among patients with advanced malignancy with incidence rates of 28‐51% for gastrointestinal and gynecological cancers. This condition may signify a terminal event with an associated median life expectancy of 4 months. Therefore, goals of care for this high‐risk population are palliative requiring careful consideration of patient quality of life through either medical or surgical treatment approaches. Despite the potential palliative benefits of surgery for patients with malignant bowel obstruction, surgery is associated with rates of serious complications as high as 44%. Furthermore, these patients are at risk for prolonged hospitalization which may consume a considerable percentage of their limited life expectancy. Therefore, careful surgical risk stratification is essential for informed consent prior to proceeding with surgical intervention.Traditional methods of operative risk stratification include the American Society of Anesthesiologist (ASA) physical status classification and the Charlson comorbidity index (CCI). In addition, a growing body of research has demonstrated the use of measures of frailty, including the modified frailty index (mFI), to predict postoperative morbidity and mortality for numerous surgical interventions including pancreatectomy, hepatectomy, and colorectal surgery. Frailty is defined as decreased physiologic reserve and, therefore, increased vulnerability to disability due to inability to withstand stressors. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Surgical Oncology Wiley

Comparison of common risk stratification indices to predict outcomes among stage IV cancer patients with bowel obstruction undergoing surgery

Loading next page...
 
/lp/wiley/comparison-of-common-risk-stratification-indices-to-predict-outcomes-sLuUUiJohY
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 Wiley Periodicals, Inc.
ISSN
0022-4790
eISSN
1096-9098
D.O.I.
10.1002/jso.24866
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTIONMalignant bowel obstruction is common among patients with advanced malignancy with incidence rates of 28‐51% for gastrointestinal and gynecological cancers. This condition may signify a terminal event with an associated median life expectancy of 4 months. Therefore, goals of care for this high‐risk population are palliative requiring careful consideration of patient quality of life through either medical or surgical treatment approaches. Despite the potential palliative benefits of surgery for patients with malignant bowel obstruction, surgery is associated with rates of serious complications as high as 44%. Furthermore, these patients are at risk for prolonged hospitalization which may consume a considerable percentage of their limited life expectancy. Therefore, careful surgical risk stratification is essential for informed consent prior to proceeding with surgical intervention.Traditional methods of operative risk stratification include the American Society of Anesthesiologist (ASA) physical status classification and the Charlson comorbidity index (CCI). In addition, a growing body of research has demonstrated the use of measures of frailty, including the modified frailty index (mFI), to predict postoperative morbidity and mortality for numerous surgical interventions including pancreatectomy, hepatectomy, and colorectal surgery. Frailty is defined as decreased physiologic reserve and, therefore, increased vulnerability to disability due to inability to withstand stressors.

Journal

Journal of Surgical OncologyWiley

Published: Jan 1, 2018

Keywords: ; ; ; ;

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial