Comparative study of head and neck mucosal melanoma in 66 patients vs 226 patients with cutaneous melanoma: A survival analysis

Comparative study of head and neck mucosal melanoma in 66 patients vs 226 patients with cutaneous... KeypointsSixty‐six patients (22%) had head and neck mucosal melanoma (HNMM) and 226 (78%) head and neck cutaneous melanoma (HNCM), and the higher prevalence was seen in females with a similar distribution amongst the two diagnoses (P = .8).Symptoms were present in all patients with HNCM and in only 15% of patients with HNMM (P = .000).Lymph node involvement at diagnosis was present in 51% of HNMM vs 33% of HNCM (P = .007) and was bilateral in 44% of HNMM while in HNCM they were only ipsilateral (P = .000).Metastatic disease at diagnosis was similar in both groups (P = .9).Relapses were more frequent in the HNMM group in ˜70% of the cases compared with 23% in HNCM group (P = .000).When comparing HNCM vs HNMM, overall survival is similar, without statistical difference.INTRODUCTIONMelanoma is a neoplasm that results from the malignant transformation of melanocytes. Despite being one of the less frequent malignant neoplasms of the skin, it has shown an increased incidence in the last years. According to the Surveillance, Epidemiology and End Results (SEER) program of the National Cancer Institute (NCI), the annual percentage of new cases is 4.5%, with a mortality rate of 1.7%. Cutaneous melanomas (CM) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Otolaryngology Wiley

Comparative study of head and neck mucosal melanoma in 66 patients vs 226 patients with cutaneous melanoma: A survival analysis

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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 John Wiley & Sons Ltd
ISSN
1749-4478
eISSN
1749-4486
D.O.I.
10.1111/coa.13000
Publisher site
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Abstract

KeypointsSixty‐six patients (22%) had head and neck mucosal melanoma (HNMM) and 226 (78%) head and neck cutaneous melanoma (HNCM), and the higher prevalence was seen in females with a similar distribution amongst the two diagnoses (P = .8).Symptoms were present in all patients with HNCM and in only 15% of patients with HNMM (P = .000).Lymph node involvement at diagnosis was present in 51% of HNMM vs 33% of HNCM (P = .007) and was bilateral in 44% of HNMM while in HNCM they were only ipsilateral (P = .000).Metastatic disease at diagnosis was similar in both groups (P = .9).Relapses were more frequent in the HNMM group in ˜70% of the cases compared with 23% in HNCM group (P = .000).When comparing HNCM vs HNMM, overall survival is similar, without statistical difference.INTRODUCTIONMelanoma is a neoplasm that results from the malignant transformation of melanocytes. Despite being one of the less frequent malignant neoplasms of the skin, it has shown an increased incidence in the last years. According to the Surveillance, Epidemiology and End Results (SEER) program of the National Cancer Institute (NCI), the annual percentage of new cases is 4.5%, with a mortality rate of 1.7%. Cutaneous melanomas (CM)

Journal

Clinical OtolaryngologyWiley

Published: Jan 1, 2018

References

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