Clinical illness due to parvovirus B19 infection after infusion of solvent/detergent‐treated pooled plasma

Clinical illness due to parvovirus B19 infection after infusion of solvent/detergent‐treated... BACKGROUND: Lipid‐enveloped viruses such as HIV, HBV, and HCV can be inactivated by treatment with solvents and detergents. HAV and human parvovirus B19 lack lipid envelopes and are not inactivated. Solvent/detergent‐treated pooled plasma (S/D plasma) contains neutralizing antibodies, but it is not known whether the parvovirus B19 antibody content is sufficient to prevent transmission of the disease. A patient is described who developed a clinical illness due to parvovirus B19 infection after the infusion of S/D plasma. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Transfusion Wiley

Clinical illness due to parvovirus B19 infection after infusion of solvent/detergent‐treated pooled plasma

Transfusion, Volume 40 (10) – Jan 1, 2000

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Publisher
Wiley
Copyright
Copyright © 2000 Wiley Subscription Services
ISSN
0041-1132
eISSN
1537-2995
DOI
10.1046/j.1537-2995.2000.40101203.x
Publisher site
See Article on Publisher Site

Abstract

BACKGROUND: Lipid‐enveloped viruses such as HIV, HBV, and HCV can be inactivated by treatment with solvents and detergents. HAV and human parvovirus B19 lack lipid envelopes and are not inactivated. Solvent/detergent‐treated pooled plasma (S/D plasma) contains neutralizing antibodies, but it is not known whether the parvovirus B19 antibody content is sufficient to prevent transmission of the disease. A patient is described who developed a clinical illness due to parvovirus B19 infection after the infusion of S/D plasma.

Journal

TransfusionWiley

Published: Jan 1, 2000

Keywords: ; ; ; ;

References

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