P398Trial of FreeStyle Libre flash glucose monitoring (FGM) in patients with poorly controlled Type 1 diabetesK MITCHELL and C McDougallDepartment of Diabetes, Hairmyres Hospital, NHS Lanarkshire, East Kilbride, UKBackground/AimsThe Freestyle Libre FGM system measures interstitial fluid glucose and records an ambulatory glucose profile. Previous studies have demonstrated improvement in HbA1c, frequency of hypoglycaemia and quality of life in patients with moderately controlled Type 1 diabetes. This study aimed to assess the impact of FGM on these parameters in patients with Type 1 diabetes with poor glycaemic control (HbA1c ≥75mmol/mol).Methods: Sixteen patients (62.5% female) with Type 1 diabetes were studied (mean ± SD: age 33.6 ± 14.7 years, duration of diabetes 16.6 ± 10.7 years). Participants used the FGM system rather than traditional home BGM devices and were followed up for over a 12‐week period. HbA1c, quality of life (problem areas in diabetes [PAID] scale), frequency of glucose monitoring and frequency of hypoglycaemia (glucose <4mmol/l) were measured at baseline and after 12 weeks.Results: Thirteen patients (81.3%) completed the study. At 12‐week follow‐up, there was a reduction in mean HbA1c (pre 88.8mmol/mol vs post 78.7mmol/mol, mean reduction [95% confidence interval] = 9.62mmol/mol [5.56 to 13.67], p < 0.001), a reduction in PAID score (pre 39.5 vs post 26.2, mean reduction 11.1 [1.7 to
Diabetic Medicine – Wiley
Published: Jan 1, 2018
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