IntroductionAtopic dermatitis (AD) is the most common inflammatory skin disease of childhood. It has a common phenotypic expression, characterized by dry and itchy skin with chronic or recurrent episodes of dermatitis at typical anatomical sites. The prevalence of AD has dramatically increased over the last three decades and now affects between 15% and 30% of children in Western countries.Allergic contact dermatitis (ACD) is the skin manifestation of a delayed‐type hypersensitivity reaction that typically develops after prolonged or repeated skin exposure to chemical allergens. Although previously considered rare, it is now recognized as a common skin disease in children. Clinically, AD and allergic contact dermatitis may be difficult to distinguish as they both present as dermatitis and may co‐exist. Whether children with AD have an altered risk of contact allergy as compared to children without AD is frequently discussed and past findings have been conflicting. Authors of early experimental studies found reduced sensitization among patients with AD as compared to controls, but recent research suggests that contact allergy and allergic contact dermatitis may be a significant problem in AD patients. The impaired skin barrier in AD facilitates the penetration of potential allergens and as children with AD are exposed to
Journal of the European Academy of Dermatology & Venereology – Wiley
Published: Jan 1, 2018
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