Changes in Diapered and Nondiapered Infant Skin Over the First Month of Life

Changes in Diapered and Nondiapered Infant Skin Over the First Month of Life Abstract: Time‐ and site‐dependent differences in epidermal barrier properties were investigated over the first 28 days of life in healthy term newborn infants. Diapered and nondiapered skin sites were contrasted to the volar forearm of adults (mothers). Thirty‐one term infants were evaluated in the hospital on postnatal day 1 and at home on days 4, 7, 14, 21, and 28 for a total of six visits. Measurements included baseline skin hydration, continuous capacitive reactance, peak water sorption, rate of water desorption, skin pH, skin temperature, and environmental conditions. Changes in epidermal barrier properties over the first 4 weeks of life included an increase in surface hydration, a decrease in transepidermal water movement under occlusion, a decrease in surface water desorption rate, and a decrease in surface pH. Diapered and nondiapered regions were indistinguishable at birth but exhibited differential behavior over the first 14 days, with the diapered region showing a higher pH and increased hydration. Maternal measurements remained constant throughout the period. We conclude that healthy newborn skin undergoes progressive changes in epidermal barrier properties over the first 28 days. Adult skin testing does not replicate newborn skin during the first month of life. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pediatric Dermatology Wiley

Changes in Diapered and Nondiapered Infant Skin Over the First Month of Life

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Publisher
Wiley
Copyright
Copyright © 2000 Wiley Subscription Services
ISSN
0736-8046
eISSN
1525-1470
D.O.I.
10.1046/j.1525-1470.2000.01711.x
Publisher site
See Article on Publisher Site

Abstract

Abstract: Time‐ and site‐dependent differences in epidermal barrier properties were investigated over the first 28 days of life in healthy term newborn infants. Diapered and nondiapered skin sites were contrasted to the volar forearm of adults (mothers). Thirty‐one term infants were evaluated in the hospital on postnatal day 1 and at home on days 4, 7, 14, 21, and 28 for a total of six visits. Measurements included baseline skin hydration, continuous capacitive reactance, peak water sorption, rate of water desorption, skin pH, skin temperature, and environmental conditions. Changes in epidermal barrier properties over the first 4 weeks of life included an increase in surface hydration, a decrease in transepidermal water movement under occlusion, a decrease in surface water desorption rate, and a decrease in surface pH. Diapered and nondiapered regions were indistinguishable at birth but exhibited differential behavior over the first 14 days, with the diapered region showing a higher pH and increased hydration. Maternal measurements remained constant throughout the period. We conclude that healthy newborn skin undergoes progressive changes in epidermal barrier properties over the first 28 days. Adult skin testing does not replicate newborn skin during the first month of life.

Journal

Pediatric DermatologyWiley

Published: Jan 1, 2000

References

  • Association of skin wetness and pH with diaper dermatitis.
    Berg, RW; Milligan, MC; Sarbaugh, FC
  • Handbook of noninvasive methods and the skin
    Serup, J; Jemec, G
  • Diaper performance: maintenance of healthy skin.
    Wilson, PA; Dallas, MJ
  • The relationship of diapers to diaper rashes in the one‐month‐old infant.
    Wiener, F

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