BLOOD SCREENING FOR NON‐A, NON‐B HEPATITIS BY HEPATITIS C VIRUS ANTIBODY ASSAY

BLOOD SCREENING FOR NON‐A, NON‐B HEPATITIS BY HEPATITIS C VIRUS ANTIBODY ASSAY ABSTRACT: Hepatitis C virus (HCV) antibody was detected in 1499 donor sera by radioimmunoassay using an antigen expressed in yeast from a cDNA clone of the HCV genome. Eighteen samples over 4200 counts per minute (cpm) were considered to contain infectious HCV because these recipients developed typical posttransfusion non‐A,non‐B hepatitis after transfusion. The antibody‐positive sera were all within the normal range of ALT levels. This assay system is thus useful for the screening for blood transfusion. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Transfusion Wiley

BLOOD SCREENING FOR NON‐A, NON‐B HEPATITIS BY HEPATITIS C VIRUS ANTIBODY ASSAY

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Publisher
Wiley
Copyright
1990 AABB
ISSN
0041-1132
eISSN
1537-2995
D.O.I.
10.1046/j.1537-2995.1990.30490273448.x
Publisher site
See Article on Publisher Site

Abstract

ABSTRACT: Hepatitis C virus (HCV) antibody was detected in 1499 donor sera by radioimmunoassay using an antigen expressed in yeast from a cDNA clone of the HCV genome. Eighteen samples over 4200 counts per minute (cpm) were considered to contain infectious HCV because these recipients developed typical posttransfusion non‐A,non‐B hepatitis after transfusion. The antibody‐positive sera were all within the normal range of ALT levels. This assay system is thus useful for the screening for blood transfusion.

Journal

TransfusionWiley

Published: May 1, 1990

References

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