Blood indices of muscle injury associated with eccentric muscle contractions

Blood indices of muscle injury associated with eccentric muscle contractions Serum muscle enzyme activities of eight healthy men (22–32 years old) were measured before and 48 h after separate bouts of repetitive concentric, eccentric, and isometric contractions of the lower leg anterior compartments. Serum creatine kinase and glutamic oxaloacetic acid transaminase levels were both elevated 2 days after the eccentric exercise regimen, exclusively (36 and 17%, respectively). Lactic dehydrogenase levels were not affected by any of the protocols. Delayed muscle soreness was exclusively reported from the eccentrically exercised limb. We suggest that the high tensions developed during eccentric exercise cause mechanical damage, possibly including sarcolemmal degeneration. Subsequently, muscle enzymes are released to the blood. We conclude that postexercise serum levels of some muscle enzymes, at the time of maximal soreness, are qualitative markers of muscle damage. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Orthopaedic Research Wiley

Blood indices of muscle injury associated with eccentric muscle contractions

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Publisher
Wiley
Copyright
Copyright © 1989 Orthopaedic Research Society
ISSN
0736-0266
eISSN
1554-527X
DOI
10.1002/jor.1100070120
pmid
2908906
Publisher site
See Article on Publisher Site

Abstract

Serum muscle enzyme activities of eight healthy men (22–32 years old) were measured before and 48 h after separate bouts of repetitive concentric, eccentric, and isometric contractions of the lower leg anterior compartments. Serum creatine kinase and glutamic oxaloacetic acid transaminase levels were both elevated 2 days after the eccentric exercise regimen, exclusively (36 and 17%, respectively). Lactic dehydrogenase levels were not affected by any of the protocols. Delayed muscle soreness was exclusively reported from the eccentrically exercised limb. We suggest that the high tensions developed during eccentric exercise cause mechanical damage, possibly including sarcolemmal degeneration. Subsequently, muscle enzymes are released to the blood. We conclude that postexercise serum levels of some muscle enzymes, at the time of maximal soreness, are qualitative markers of muscle damage.

Journal

Journal of Orthopaedic ResearchWiley

Published: Jan 1, 1989

References

  • Eccentric exercise‐induced injury to the rat skeletal muscle
    Armstrong, Armstrong; Ogilvie, Ogilvie; Schwane, Schwane
  • Residual muscular swelling after repetitive eccentric contractions
    Fridén, Fridén; Sfakianos, Sfakianos; Hargens, Hargens; Akeson, Akeson

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