Average heterozygosity per locus in man: an estimate based on the incidence of enzyme polymorphisms

Average heterozygosity per locus in man: an estimate based on the incidence of enzyme polymorphisms SUMMARY 1. Data from electrophoretic surveys of enzymes in European populations are reviewed. 2. Out of the seventy‐one structural gene loci determining enzyme structure which have been scrutinized electrophoretically, 20 (28 %) were found to show genetic polymorphism. The average heterozygosity per locus for alleles determining electrophoretic variants is estimated at 0·067. 3. These results are compared with data from some other species. 4. For several different reasons, most of which relate to the techniques used and the enzymes and tissues surveyed, it seems likely that the present data considerably underestimate the true incidence of polymorphism and average heterozygosity per locus. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Human Genetics Wiley

Average heterozygosity per locus in man: an estimate based on the incidence of enzyme polymorphisms

Annals of Human Genetics, Volume 36 (1) – Jul 1, 1972

Loading next page...
 
/lp/wiley/average-heterozygosity-per-locus-in-man-an-estimate-based-on-the-0k34ycWjzQ
Publisher
Wiley
Copyright
Copyright © 1972 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0003-4800
eISSN
1469-1809
D.O.I.
10.1111/j.1469-1809.1972.tb00578.x
Publisher site
See Article on Publisher Site

Abstract

SUMMARY 1. Data from electrophoretic surveys of enzymes in European populations are reviewed. 2. Out of the seventy‐one structural gene loci determining enzyme structure which have been scrutinized electrophoretically, 20 (28 %) were found to show genetic polymorphism. The average heterozygosity per locus for alleles determining electrophoretic variants is estimated at 0·067. 3. These results are compared with data from some other species. 4. For several different reasons, most of which relate to the techniques used and the enzymes and tissues surveyed, it seems likely that the present data considerably underestimate the true incidence of polymorphism and average heterozygosity per locus.

Journal

Annals of Human GeneticsWiley

Published: Jul 1, 1972

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create folders to
organize your research

Export folders, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off