Correspondence Clinical Letter AFX [4–6]. However, AFX lesions accompanied by diffuse Clinical Letter infiltration of immune cells have rarely been reported. Her - Atypical fibroxanthoma with prominent CD8- ein, we report a case of AFX with prominent infiltration of CD8-positive lymphocytes. Immunohistochemical analysis positive lymphocytic infiltration and diffuse revealed the tumor cells to diffusely express epithelial mem- expression of epithelial membrane antigen brane antigen (EMA), an extremely rare finding. A 74-year-old Japanese woman presented with a two- month history of a rapidly growing, reddish, dome-shaped, DOI: 10.1111/ddg.13406 ulcerated tumor (20 mm in diameter) on her right temple (Figure 1a). Dermatoscopic examination revealed a homoge- Dear Editors, neous red pattern with linear vessels (Figure 1b). Histopatho- logically, the exophytic tumor was characterized by a highly Atypical fibroxanthoma (AFX) is a rare, rapidly growing tu - cellular dermal mass (Figure 1c). The overlying epidermis mor of intermediate malignancy that develops on the sun-ex- was almost completely ulcerated, except for a peripheral epi- posed skin of elderly individuals. Clinically, it usually presents dermal collarette. The tumor was made up of atypical spindle as a solitary, firm, reddish papule or nodule [1, 2]. Histopa - and epithelioid cells with pleomorphic nuclei (Figure 1d).
Journal Der Deutschen Dermatologischen Gesellschaft – Wiley
Published: Jan 1, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera