INTRODUCTIONA growing proportion of individuals with type 2 diabetes mellitus (DM2) worldwide is attributed in large part to the increase in body fat mass, especially in intra‐abdominal (visceral) region. Visceral adipose tissue is regarded to be metabolically active endocrine organ, secreting a variety of pro‐inflammatory adipokines, thus further leading to many cardiometabolic disorders.Simple anthropometric parameter of abdominal adiposity such as waist circumference (WC) is established and widely used in many investigations. As early recognition and treatment of individuals with abdominal adiposity is of utmost importance in reducing cardiometabolic risk, some novel visceral adiposity markers, such as visceral adiposity index (VAI) and the lipid accumulation product (LAP) have been validated so far.The VAI is gender‐specific mathematical model that uses both anthropometric indices [e.g., body mass index (BMI) and WC] and lipid parameters [e.g., high‐density lipoprotein cholesterol (HDL‐c) and triglycerides (TG)] in its equation, and is highly correlated with visceral adiposity as measured with the gold standard method, such as magnetic resonance imaging. The LAP is a gender‐specific index based on a combination of WC and TG in its equation. Both of these indexes are proposed as simple, accurate, and low‐cost tools for the evaluation of visceral adipose tissue dysfunction and
Journal of Clinical Laboratory Analysis – Wiley
Published: Jan 1, 2018
Keywords: ; ; ;
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