INTRODUCTIONA growing proportion of individuals with type 2 diabetes mellitus (DM2) worldwide is attributed in large part to the increase in body fat mass, especially in intra‐abdominal (visceral) region. Visceral adipose tissue is regarded to be metabolically active endocrine organ, secreting a variety of pro‐inflammatory adipokines, thus further leading to many cardiometabolic disorders.Simple anthropometric parameter of abdominal adiposity such as waist circumference (WC) is established and widely used in many investigations. As early recognition and treatment of individuals with abdominal adiposity is of utmost importance in reducing cardiometabolic risk, some novel visceral adiposity markers, such as visceral adiposity index (VAI) and the lipid accumulation product (LAP) have been validated so far.The VAI is gender‐specific mathematical model that uses both anthropometric indices [e.g., body mass index (BMI) and WC] and lipid parameters [e.g., high‐density lipoprotein cholesterol (HDL‐c) and triglycerides (TG)] in its equation, and is highly correlated with visceral adiposity as measured with the gold standard method, such as magnetic resonance imaging. The LAP is a gender‐specific index based on a combination of WC and TG in its equation. Both of these indexes are proposed as simple, accurate, and low‐cost tools for the evaluation of visceral adipose tissue dysfunction and
Journal of Clinical Laboratory Analysis – Wiley
Published: Jan 1, 2018
Keywords: ; ; ;
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
All the latest content is available, no embargo periods.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud