Antioxidant and immunomodulatory activities of sulphated polysaccharides from purple glutinous rice bran (Oryza sativa L.)

Antioxidant and immunomodulatory activities of sulphated polysaccharides from purple glutinous... This research aimed to extract polysaccharides and improve the property of sulphate‐modified purple glutinous rice bran, cv. Kum Doi Saket. The effects of temperature, ratio of sulphur trioxide–trimethylamine (STMA) to sample and reaction times were studied. The results showed that the degree of substitution (DS) of sulphated polysaccharides was 0.01–0.53. Low molecular weight sulphated polysaccharides were obtained, and the functional groups of the sulphated polysaccharides were confirmed using FT‐IR. No enhancement of the antioxidant activity of the sulphated polysaccharides was observed. Interestingly, immunomodulatory activity, including inducing cytokine production (iNOS, TNF‐α, IL‐1β and IL‐10) via up‐regulated mRNA expression, was significantly increased by 10–86% when compared to the crude polysaccharides. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png International Journal of Food Science & Technology Wiley

Antioxidant and immunomodulatory activities of sulphated polysaccharides from purple glutinous rice bran (Oryza sativa L.)

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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
International Journal of Food Science and Technology © 2018 Institute of Food Science and Technology
ISSN
0950-5423
eISSN
1365-2621
D.O.I.
10.1111/ijfs.13674
Publisher site
See Article on Publisher Site

Abstract

This research aimed to extract polysaccharides and improve the property of sulphate‐modified purple glutinous rice bran, cv. Kum Doi Saket. The effects of temperature, ratio of sulphur trioxide–trimethylamine (STMA) to sample and reaction times were studied. The results showed that the degree of substitution (DS) of sulphated polysaccharides was 0.01–0.53. Low molecular weight sulphated polysaccharides were obtained, and the functional groups of the sulphated polysaccharides were confirmed using FT‐IR. No enhancement of the antioxidant activity of the sulphated polysaccharides was observed. Interestingly, immunomodulatory activity, including inducing cytokine production (iNOS, TNF‐α, IL‐1β and IL‐10) via up‐regulated mRNA expression, was significantly increased by 10–86% when compared to the crude polysaccharides.

Journal

International Journal of Food Science & TechnologyWiley

Published: Jan 1, 2018

Keywords: ; ; ; ;

References

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