Antimicrobial effectiveness of combinations of oxidant and chelating agents in infected dentine: an ex vivo confocal laser scanning microscopy study

Antimicrobial effectiveness of combinations of oxidant and chelating agents in infected dentine:... IntroductionSuccessful root canal treatment depends on many factors, including the quality of canal instrumentation and irrigation. Several studies have reported poor debridement of the root canal regardless of the instrumentation technique used (Paqué et al. , Peters et al. , Paqué & Peters ). For this reasons, both instruments and irrigants are used in conjunction to achieve thorough canal debridement (Baker et al. ). The most commonly used irrigating solutions are sodium hypochlorite (NaOCl) and ethylenediaminetetraacetic acid (EDTA) (Scelza et al. , Zehnder ).NaOCl is the most widely used irrigating solution in endodontics for its antimicrobial activity, tissue‐dissolving property, detergent action and the ability to neutralize toxic products (Mohammadi ). One of the major drawbacks of NaOCl is its high surface tension, which limits its penetration into irregularities of the root canal system such as fins, isthmuses and dentinal tubules (Giardino et al. ). Another drawback of NaOCl is that it does not exert any residual antimicrobial activity (Mohammadi et al. ) so that recolonization of persistent microorganisms cannot be prevented.Sodium hypochlorite cannot remove the mineral content of smear layer that forms on canal walls during manual or rotary instrumentation. Therefore, EDTA solution has been suggested as an irrigant because it can chelate and remove http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png International Endodontic Journal Wiley

Antimicrobial effectiveness of combinations of oxidant and chelating agents in infected dentine: an ex vivo confocal laser scanning microscopy study

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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
Copyright © 2018 International Endodontic Journal. Published by John Wiley & Sons Ltd
ISSN
0143-2885
eISSN
1365-2591
D.O.I.
10.1111/iej.12863
Publisher site
See Article on Publisher Site

Abstract

IntroductionSuccessful root canal treatment depends on many factors, including the quality of canal instrumentation and irrigation. Several studies have reported poor debridement of the root canal regardless of the instrumentation technique used (Paqué et al. , Peters et al. , Paqué & Peters ). For this reasons, both instruments and irrigants are used in conjunction to achieve thorough canal debridement (Baker et al. ). The most commonly used irrigating solutions are sodium hypochlorite (NaOCl) and ethylenediaminetetraacetic acid (EDTA) (Scelza et al. , Zehnder ).NaOCl is the most widely used irrigating solution in endodontics for its antimicrobial activity, tissue‐dissolving property, detergent action and the ability to neutralize toxic products (Mohammadi ). One of the major drawbacks of NaOCl is its high surface tension, which limits its penetration into irregularities of the root canal system such as fins, isthmuses and dentinal tubules (Giardino et al. ). Another drawback of NaOCl is that it does not exert any residual antimicrobial activity (Mohammadi et al. ) so that recolonization of persistent microorganisms cannot be prevented.Sodium hypochlorite cannot remove the mineral content of smear layer that forms on canal walls during manual or rotary instrumentation. Therefore, EDTA solution has been suggested as an irrigant because it can chelate and remove

Journal

International Endodontic JournalWiley

Published: Jan 1, 2018

Keywords: ; ; ; ;

References

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