Analgesic effects of local anesthetic cream in cryotherapy for warts: a meta‐analysis of randomized trials

Analgesic effects of local anesthetic cream in cryotherapy for warts: a meta‐analysis of... IntroductionWarts are caused by infection with human papillomavirus (HPV) , and are one of the most common skin diseases. Warts can occur on hardened skin (e. g. palms, soles, and periungual area) or on nonhardened skin (e. g. genital area) . The appearance of warts varies depending on the type of the causal HPV and the affected area . Cryotherapy is commonly employed for removing warts ; it employs low temperature agents such as liquid nitrogen to produce controlled cryoinjury and destroy lesional cells on the surface of the skin . However, cryotherapy needs several treatment sessions and may lead to pain and other side effects, such as injury to underlying structures and scarring . Occasionally the pain is so severe that application of cryotherapy must be interrupted, resulting in treatment failure – especially in patients who are intolerant to pain (such as children) .Local anesthetic cream (LAC) is used as a topical anesthetic on the skin and has been used to relieve pain associated with dermatologic procedures such as laser therapy . EMLA cream is the most commonly used brand of LAC and is a eutectic mixture of 2.5 % lidocaine and 2.5 % prilocaine . The analgesic effect of EMLA cream http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal Der Deutschen Dermatologischen Gesellschaft Wiley

Analgesic effects of local anesthetic cream in cryotherapy for warts: a meta‐analysis of randomized trials

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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.
ISSN
1610-0379
eISSN
1610-0387
D.O.I.
10.1111/ddg.13452
Publisher site
See Article on Publisher Site

Abstract

IntroductionWarts are caused by infection with human papillomavirus (HPV) , and are one of the most common skin diseases. Warts can occur on hardened skin (e. g. palms, soles, and periungual area) or on nonhardened skin (e. g. genital area) . The appearance of warts varies depending on the type of the causal HPV and the affected area . Cryotherapy is commonly employed for removing warts ; it employs low temperature agents such as liquid nitrogen to produce controlled cryoinjury and destroy lesional cells on the surface of the skin . However, cryotherapy needs several treatment sessions and may lead to pain and other side effects, such as injury to underlying structures and scarring . Occasionally the pain is so severe that application of cryotherapy must be interrupted, resulting in treatment failure – especially in patients who are intolerant to pain (such as children) .Local anesthetic cream (LAC) is used as a topical anesthetic on the skin and has been used to relieve pain associated with dermatologic procedures such as laser therapy . EMLA cream is the most commonly used brand of LAC and is a eutectic mixture of 2.5 % lidocaine and 2.5 % prilocaine . The analgesic effect of EMLA cream

Journal

Journal Der Deutschen Dermatologischen GesellschaftWiley

Published: Jan 1, 2018

References

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