No. 6 Adenine and Purine Nucleosides in Human Red Cell Preservation: A Review E. R. SIMON From the Department of Medicine, University of N e w Mexico School Albuquerque, N e w Mexico of Medicine ON THE RECOMMENDATION of the National Research Council, a developmental program is being conducted to extend the useful shelf-life and to establish the safety and efficacy of whole blood and of sedimented red cells at refrigerator temperatures (1 to 6 C) by adenine-supplemented preservative media. About 18 months ago the Army Medical Research and Develop ment Command, which has encouraged and supported basic research on this problem since the mid-l950âs, embarked on a large intramural and extramural program to investigate the use of such blood in the treatment of traumatic shock. More recently, the National Blood Resource Program, National Heart Institute, also initiated a major program to augment the Armyâs efforts and to expand the scope Received for publication August 30, 1967; accepted October 12, 1967. Studies summarized in this review, which were performed in the authorâs laboratory, were supported in part by contracts DA-49-007-MD-508and DA-49-193-MD-2333from the U. S. Army Medical Research and Development Command, Office of the Surgeon General, and grant AM-08131
Transfusion – Wiley
Published: Nov 12, 1967
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