Acrosclerosis Associated with Vibration: an Electron Microscopic Study

Acrosclerosis Associated with Vibration: an Electron Microscopic Study A case of typical vibration‐induced acrosclerosis was studied with the electron microscope. In addition to increased collagenization of the dermis, vascular wall and perivascular spaces, a severe vacuolization and an increased number of lysosomes in the vascular endothelial cells were observed. In many peripheral nerves, axonal degeneration, demyelination and an extensive collagenization of peri‐ and endoneurium were observed. These changes appeared to be the organic basis for sclerosis and neuropathies of this condition. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Cutaneous Pathology Wiley

Acrosclerosis Associated with Vibration: an Electron Microscopic Study

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Publisher
Wiley
Copyright
Copyright © 1980 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0303-6987
eISSN
1600-0560
DOI
10.1111/j.1600-0560.1980.tb01211.x
Publisher site
See Article on Publisher Site

Abstract

A case of typical vibration‐induced acrosclerosis was studied with the electron microscope. In addition to increased collagenization of the dermis, vascular wall and perivascular spaces, a severe vacuolization and an increased number of lysosomes in the vascular endothelial cells were observed. In many peripheral nerves, axonal degeneration, demyelination and an extensive collagenization of peri‐ and endoneurium were observed. These changes appeared to be the organic basis for sclerosis and neuropathies of this condition.

Journal

Journal of Cutaneous PathologyWiley

Published: Dec 1, 1980

References

  • Fibrinogen turnover in progressive systemic sclerosis
    Gratwick, Gratwick; Klein, Klein; Sergent, Sergent; Christian, Christian
  • Endothelial injury in scleroderma
    Kahaleh, Kahaleh; Sherer, Sherer; LeRoy, LeRoy
  • The use of lead citrate at high pH as an electron‐opaque stain in electron microscopy
    Reynolds, Reynolds

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