Letters to the Editor (a) (b) (c) Figure 1. (a) Lower legs of the patient. Depigmented spots are scattered in well- demarcated pigmented areas in both lower legs. A large skin ulcer is distributed (d) almost around the lower half of her left leg (arrows). Scratched marks are also pre- sent around the ulcer. (b) Small, red, ten- der nodule on the left leg (arrow). (c) Histological changes of the skin ulcer lesion (hematoxylin–eosin [HE], original magniﬁcation 940). (d) Chronic granula- tion changes in the adjacent area of the ulcer (HE, 9400). 5 3 detected. On the other hand, epithelioid granuloma was not and Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan detected in the present case, whereas dermal cicatrization with recurrent EN may disturb local circulation. doi: 10.1111/1346-8138.13345 Although she noticed no apparent skin injury, her skin was dry and itchy and, therefore, scratching-induced microtrauma REFERENCES might have been a trigger for ulceration. In conclusion, we reported a rare familial case of BS with 1 Blau EB. Familial granulomatous arthritis, iritis, and rash. J Pediatr intractable leg ulcers. BS may cause intractable leg ulcers, in 1985; 107: 689–693. 2 Miceli-Richard C, Lesage S, Rybojad
The Journal of Dermatology – Wiley
Published: Sep 1, 2016
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