A Western dietary pattern is associated with elevated level of high sensitive C‐reactive protein among adolescent girls

A Western dietary pattern is associated with elevated level of high sensitive C‐reactive... INTRODUCTIONA state of low‐grade inflammation is associated with several non‐communicable conditions that include obesity, diabetes, metabolic syndrome and cardiovascular disease (CVD). Serum high sensitivity C‐reactive protein (hs‐CRP) is a well‐known inflammatory marker, which is secreted by liver under the control of interleukin 6 (IL‐6) and appears to be associated with several chronic diseases in both young people and adults.It has been shown that the origin of atherosclerosis begins in childhood and after progression, its clinical symptoms may appear in young adulthood. In a previous study, it has been reported that there is a significant association between aortic pulse wave velocity (aPWV), one of the most often used measures of arterial stiffness and serum hs‐CRP concentrations in young people who are either obese or have type 2 diabetes. Several factors include smoking, BMI, waist circumferences and physical inactivity have been shown to be directly related to serum hs‐CRP in both young people and adults; the role of diet in influencing serum hs‐CRP, particularly among adolescents, remains unclear. A randomized controlled trial has shown that lifestyle modification, that included diet and physical activity, reduced serum hs‐CRP, IL‐6 and fibrinogen significantly in obese adolescents. However, there are little data on the relationship http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Clinical Investigation Wiley
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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
Copyright © 2018 Stichting European Society for Clinical Investigation Journal Foundation. Published by John Wiley & Sons Ltd
ISSN
0014-2972
eISSN
1365-2362
D.O.I.
10.1111/eci.12897
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTIONA state of low‐grade inflammation is associated with several non‐communicable conditions that include obesity, diabetes, metabolic syndrome and cardiovascular disease (CVD). Serum high sensitivity C‐reactive protein (hs‐CRP) is a well‐known inflammatory marker, which is secreted by liver under the control of interleukin 6 (IL‐6) and appears to be associated with several chronic diseases in both young people and adults.It has been shown that the origin of atherosclerosis begins in childhood and after progression, its clinical symptoms may appear in young adulthood. In a previous study, it has been reported that there is a significant association between aortic pulse wave velocity (aPWV), one of the most often used measures of arterial stiffness and serum hs‐CRP concentrations in young people who are either obese or have type 2 diabetes. Several factors include smoking, BMI, waist circumferences and physical inactivity have been shown to be directly related to serum hs‐CRP in both young people and adults; the role of diet in influencing serum hs‐CRP, particularly among adolescents, remains unclear. A randomized controlled trial has shown that lifestyle modification, that included diet and physical activity, reduced serum hs‐CRP, IL‐6 and fibrinogen significantly in obese adolescents. However, there are little data on the relationship

Journal

European Journal of Clinical InvestigationWiley

Published: Jan 1, 2018

Keywords: ; ; ;

References

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