A real‐time prediction model for post‐irradiation malignant cervical lymph nodes

A real‐time prediction model for post‐irradiation malignant cervical lymph nodes KeypointsA predictive scoring model can help identifying post‐irradiated nodal metastasisA score can be automatically calculated after filling in all the parametersFine needle aspiration should be done for a high‐risk LNINTRODUCTIONHead and neck surgeons often encounter a history of previous neck irradiation during the assessment of patients with cancer, and early diagnosis of malignant neck node in an irradiated neck can be very challenging because fibrosis of the overlying soft tissue may mask the underlying deep‐seated lymphadenopathy. Moreover, lymphoid tissues within lymph nodes (LNs) are gradually lost and replaced by fibrous tissue as the radiation dose increases.Ultrasound (US) is a safe, cost‐effective, reliable, and widely used imaging modality to assess cervical LNs, and several sonographic characteristics have been established to help identify malignant cervical LNs, eg, size, shape, margin, echogenic hilum, vascular pattern, internal echo, and elastography. However, no single parameter has exhibited acceptable sensitivity and specificity for predicting malignant nodal disease. US‐guided fine‐needle aspiration (USgFNA) is a well‐established technique and widely accepted as an effective method for diagnosing cervical lesions. Two meta‐analyses showed that the combination of US and FNA to evaluate neck masses or LNs resulted in sensitivity and specificity values of more than 90%.In 2010, we proposed http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Otolaryngology Wiley

A real‐time prediction model for post‐irradiation malignant cervical lymph nodes

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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
© 2018 John Wiley & Sons Ltd
ISSN
1749-4478
eISSN
1749-4486
D.O.I.
10.1111/coa.12998
Publisher site
See Article on Publisher Site

Abstract

KeypointsA predictive scoring model can help identifying post‐irradiated nodal metastasisA score can be automatically calculated after filling in all the parametersFine needle aspiration should be done for a high‐risk LNINTRODUCTIONHead and neck surgeons often encounter a history of previous neck irradiation during the assessment of patients with cancer, and early diagnosis of malignant neck node in an irradiated neck can be very challenging because fibrosis of the overlying soft tissue may mask the underlying deep‐seated lymphadenopathy. Moreover, lymphoid tissues within lymph nodes (LNs) are gradually lost and replaced by fibrous tissue as the radiation dose increases.Ultrasound (US) is a safe, cost‐effective, reliable, and widely used imaging modality to assess cervical LNs, and several sonographic characteristics have been established to help identify malignant cervical LNs, eg, size, shape, margin, echogenic hilum, vascular pattern, internal echo, and elastography. However, no single parameter has exhibited acceptable sensitivity and specificity for predicting malignant nodal disease. US‐guided fine‐needle aspiration (USgFNA) is a well‐established technique and widely accepted as an effective method for diagnosing cervical lesions. Two meta‐analyses showed that the combination of US and FNA to evaluate neck masses or LNs resulted in sensitivity and specificity values of more than 90%.In 2010, we proposed

Journal

Clinical OtolaryngologyWiley

Published: Jan 1, 2018

Keywords: ; ; ; ; ;

References

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