A preliminary evaluation of the relationship between bioconcentration and hydrophobicity for surfactants

A preliminary evaluation of the relationship between bioconcentration and hydrophobicity for... A statistical analysis was done of the relationship between hydrophobicity and bioconcentration parameters (uptake and elimination rate constants and bioconcentration factor) predicted by the diffusive mass‐transfer (DMT) concept of bioconcentration developed previously. We employed polychlorinated biphenyls and benzenes (PCB/zs) as model compounds and the octanol/water partition coefficient as hydrophobicity parameter. We conclude that the model is consistent with the data. Subsequently, we applied the DMT concept to a set of preliminary bioconcentration data for surfactants using the critical micelle concentration (CMC) as hydrophobicity parameter. The obtained relationships qualitatively agree with the DMT concept, indicating that hydrophobicity is of great influence on surfactant bioconcentration. Finally, we investigated the hydrophobicity‐bioconcentration relationships of surfactants and PCB/zs using aqueous solubility as common hydrophobicity parameter and found the relationships between the bioconcentration parameters and hydrophobicity to agree with the DMT concept. These findings are based on total radiolabel data. Therefore, they need to be confirmed using compound‐specific surfactant bioconcentration data. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Environmental Toxicology & Chemistry Wiley

A preliminary evaluation of the relationship between bioconcentration and hydrophobicity for surfactants

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Publisher
Wiley
Copyright
Copyright © 1995 SETAC
ISSN
0730-7268
eISSN
1552-8618
DOI
10.1002/etc.5620141007
Publisher site
See Article on Publisher Site

Abstract

A statistical analysis was done of the relationship between hydrophobicity and bioconcentration parameters (uptake and elimination rate constants and bioconcentration factor) predicted by the diffusive mass‐transfer (DMT) concept of bioconcentration developed previously. We employed polychlorinated biphenyls and benzenes (PCB/zs) as model compounds and the octanol/water partition coefficient as hydrophobicity parameter. We conclude that the model is consistent with the data. Subsequently, we applied the DMT concept to a set of preliminary bioconcentration data for surfactants using the critical micelle concentration (CMC) as hydrophobicity parameter. The obtained relationships qualitatively agree with the DMT concept, indicating that hydrophobicity is of great influence on surfactant bioconcentration. Finally, we investigated the hydrophobicity‐bioconcentration relationships of surfactants and PCB/zs using aqueous solubility as common hydrophobicity parameter and found the relationships between the bioconcentration parameters and hydrophobicity to agree with the DMT concept. These findings are based on total radiolabel data. Therefore, they need to be confirmed using compound‐specific surfactant bioconcentration data.

Journal

Environmental Toxicology & ChemistryWiley

Published: Oct 1, 1995

References

  • Bioconcentration of hydrophobic chemicals in fish Relationship with membrane permeation
    Gobas, Gobas; Opperhuizen, Opperhuizen; Hutzinger, Hutzinger
  • Dynamics of hydrophobic organic chemical bioconcentration in fish
    Gobas, Gobas; Mackay, Mackay
  • Rate limiting barriers to xenobiotic uptake by the gill
    Hayton, Hayton; Barron, Barron
  • Bioconcentration of polybrominated benzenes and related superhydrophobic chemicals in fish Role of bioavailability and elimination into the feces
    Gobas, Gobas; Clark, Clark; Shiu, Shiu; Mackay, Mackay

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