Access the full text.
Sign up today, get DeepDyve free for 14 days.
F. Pitts, C. Quick (1967)
BRAIN SUCCINATE SEMIALDEHYDE DEHYDROGENASE—II. CHANGES IN THE DEVELOPING RAT BRAINJournal of Neurochemistry, 14
K. Aoki, F. Siegel (1970)
Hyperphenylalaninemia: Disaggregation of Brain Polyribosomes in Young RatsScience, 168
P. Wong, P. Justice (1972)
Effect of Amino Acid Imbalance on Polyribosome Profiles and Protein Synthesis in Fetal Cerebral Cortex
L. Austin, O. Lowry, J. Brown, J. Carter (1972)
The turnover of protein in discrete areas of rat brain.The Biochemical journal, 126 2
P. Garlick, I. Marshall (1972)
A TECHNIQUE FOR MEASURING BRAIN PROTEIN SYNTHESISJournal of Neurochemistry, 19
(1967)
Sphinyolipids, Sphinyolipidases, und Allied Disorders
R. Blasberg, A. Lajtha (1965)
Substrate specificity of steady-state amino acid transport in mouse brain slicesArchives of Biochemistry and Biophysics, 112
K. Seta, M. Sansur, A. Lajtha (1973)
The rate of incorporation of amino acids into brain proteins during infusion in the rat.Biochimica et biophysica acta, 294 1
M. Patterson, R. Greene (1965)
MEASUREMENT OF LOW ENERGY BETA-EMITTERS IN AQUEOUS SOLUTION BY LIQUID SCINTILLATION COUNTING OF EMULSIONS.Analytical chemistry, 37
E. Henshaw, C. Hirsch, B. Morton, H. Hiatt (1971)
Control of protein synthesis in mammalian tissues through changes in ribosome activity.The Journal of biological chemistry, 246 2
D. Dunlop, W. Elden, A. Lajtha (1974)
MEASUREMENTS OF RATES OF PROTEIN SYNTHESIS IN RAT BRAIN SLICESJournal of Neurochemistry, 22
A. Patel, R. Balázs (1970)
MANIFESTATION OF METABOLIC COMPARTMENTATION DURING THE MATURATION OF THE RAT BRAINJournal of Neurochemistry, 17
A. Vernadakis, N. Weiner (2012)
Drugs and the Developing Brain
(1973)
Biochitn . biophys
A. Lajtha, D. Dunlop (1974)
ALTERATIONS OF PROTEIN METABOLISM DURING DEVELOPMENT OF THE BRAIN
Abstract— The injection of large quantities of radioactive amino acid precursor is proposed as a technique for determining rates of cerebral protein synthesis in vivo. In this way the specific radioactivity of the amino acid precursor in the brain is maintained at a relatively constant level for at least 2 h. Injections of 10–15 μ mol of valine per g body weight result in nearly constant rates of incorporation of radioactivity and do not appear to inhibit cerebral protein synthesis in adult or young (2–6 day old) rat brain. Similar rates were obtained in young rat brain with lysine and histidine. Rates of protein synthesis in cerebral hemisphere were for 2‐day‐olds 2·1 per cent replacement of protein bound amino acid per h and for adult 0·62 per cent per h. Advantages and disadvantages of the procedure are discussed.
Journal of Neurochemistry – Wiley
Published: Feb 1, 1975
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.