A massive arterial thrombosis of a free anterolateral thigh flap in a patient with antiphospholipid syndrome

A massive arterial thrombosis of a free anterolateral thigh flap in a patient with... The antiphospholipid syndrome is a pathological condition characterized by recurrent thrombotic manifestations in venous and/or arterial vascular systems and by peculiar laboratory findings as anticardiolipin antibodies and/or positive lupus anticoagulant. We present a case of massive pedicle thrombosis of a free anterolateral thigh perforator flap used for tongue reconstruction following hemiglossectomy in a patient with antiphospholipid syndrome, which compelled us to an immediate second reconstruction choice with a radial forearm free flap. This case is an example of how this syndrome, especially if unknown before surgery, can influence the outcome of microsurgical transfer of flaps. © 2008 Wiley‐Liss, Inc. Microsurgery, 2008. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Microsurgery Wiley

A massive arterial thrombosis of a free anterolateral thigh flap in a patient with antiphospholipid syndrome

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Publisher
Wiley Subscription Services, Inc., A Wiley Company
Copyright
Copyright © 2008 Wiley‐Liss, Inc.
ISSN
0738-1085
eISSN
1098-2752
D.O.I.
10.1002/micr.20518
Publisher site
See Article on Publisher Site

Abstract

The antiphospholipid syndrome is a pathological condition characterized by recurrent thrombotic manifestations in venous and/or arterial vascular systems and by peculiar laboratory findings as anticardiolipin antibodies and/or positive lupus anticoagulant. We present a case of massive pedicle thrombosis of a free anterolateral thigh perforator flap used for tongue reconstruction following hemiglossectomy in a patient with antiphospholipid syndrome, which compelled us to an immediate second reconstruction choice with a radial forearm free flap. This case is an example of how this syndrome, especially if unknown before surgery, can influence the outcome of microsurgical transfer of flaps. © 2008 Wiley‐Liss, Inc. Microsurgery, 2008.

Journal

MicrosurgeryWiley

Published: Jan 1, 2008

References

  • Activation of coagulation and fibrinolysis during reconstructive microsurgery in patients with cancer
    Olsson, Olsson; Svartling, Svartling; Asko‐Seljavaara, Asko‐Seljavaara; Lassila, Lassila
  • Antiphospholipid antibodies and thrombosis
    Greaves, Greaves
  • Thrombotic manifestations of the antiphospholipid syndrome in patients with malignancies
    Miesbach, Miesbach; Scharrer, Scharrer; Asherson, Asherson
  • Thrombophilia and risk of venous thrombosis in patients with cancer
    Decousus, Decousus; Moulin, Moulin; Quenet, Quenet; Bost, Bost; Rivron‐Guillot, Rivron‐Guillot; Laporte, Laporte; Mismelti, Mismelti

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