A case of Lambert–Eaton myasthenic syndrome associated with pancreatic neuroendocrine tumor

A case of Lambert–Eaton myasthenic syndrome associated with pancreatic neuroendocrine tumor Lambert–Eaton myasthenic syndrome is an immune‐mediated disorder of the presynaptic neuromuscular junction that occurs in paraneoplastic and nontumor forms. Lambert–Eaton myasthenic syndrome is most commonly associated with small‐cell lung cancer, but has also been reported with other neuroendocrine tumors including large‐cell neuroendocrine tumor of the lung, atypical carcinoid, thymic neuroendocrine tumor, and Merkel cell carcinoma. We here report a case of electro‐diagnostically confirmed Lambert–Eaton syndrome in a patient who was found to have pancreatic neuroendocrine tumor with positive P/Q‐type calcium channel antibodies. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Neurology and Clinical Neuroscience Wiley

A case of Lambert–Eaton myasthenic syndrome associated with pancreatic neuroendocrine tumor

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Publisher
Wiley
Copyright
Copyright © 2018 Japanese Society of Neurology and John Wiley & Sons Australia, Ltd
ISSN
2049-4173
eISSN
2049-4173
D.O.I.
10.1111/ncn3.12180
Publisher site
See Article on Publisher Site

Abstract

Lambert–Eaton myasthenic syndrome is an immune‐mediated disorder of the presynaptic neuromuscular junction that occurs in paraneoplastic and nontumor forms. Lambert–Eaton myasthenic syndrome is most commonly associated with small‐cell lung cancer, but has also been reported with other neuroendocrine tumors including large‐cell neuroendocrine tumor of the lung, atypical carcinoid, thymic neuroendocrine tumor, and Merkel cell carcinoma. We here report a case of electro‐diagnostically confirmed Lambert–Eaton syndrome in a patient who was found to have pancreatic neuroendocrine tumor with positive P/Q‐type calcium channel antibodies.

Journal

Neurology and Clinical NeuroscienceWiley

Published: Jan 1, 2018

Keywords: ; ; ; ;

References

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