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References (77)
-
B. Riggs, J. Jowsey, P. Kelly, D. Hoffman, C. Arnaud (1976)
Effects of oral therapy with calcium and vitamin D in primary osteoporosis.The Journal of clinical endocrinology and metabolism, 42 6
-
B. Riis, K. Thomsen, C. Christiansen (1987)
Does calcium supplementation prevent postmenopausal bone loss? A double-blind, controlled clinical study.The New England journal of medicine, 316 4
-
N. Pocock, J. Eisman, M. Yeates, P. Sambrook, S. Eberl (1986)
Physical fitness is a major determinant of femoral neck and lumbar spine bone mineral density.The Journal of clinical investigation, 78 3
-
B. Ettinger, H. Genant, C. Cann (1985)
Long-term estrogen replacement therapy prevents bone loss and fractures.Annals of internal medicine, 102 3
-
K. Overgaard, Bente J'Riis, C. Christiansen, M. Hansen (1989)
Effect of salcatonin given intranasally on early postmenopausal bone loss.British Medical Journal, 299
-
L. Voigt, N. Weiss, N. Weiss, J. Chu, J. Chu, J. Daling, J. Daling, B. McKnight, B. McKnight, G. Belle (1991)
Progestagen supplementation of exogenous oestrogens and risk of endometrial cancerThe Lancet, 338
-
D. Kiel, D. Felson, Jennifer Anderson, P. Wilson, M. Moskowitz (1987)
Hip fracture and the use of estrogens in postmenopausal women. The Framingham Study.The New England journal of medicine, 317 19
-
B Nordin, R Heaney (1990)
Calcium supplementation of the diet: justified by present evidence.British Medical Journal, 300
-
J. Prior, YM Vigna, M. Schechter, AE Burgess (1990)
Spinal bone loss and ovulatory disturbancesInternational Journal of Gynecology & Obstetrics, 35
-
N. Watts, S. Harris, H. Genant, EDWARD Wasnich, P. Miller, R. Jackson, A. Licata, P. Ross, GRATTAN Woodson, M. Yanover, W. Mysiw, L. Kohse, M. Rao, P. Steiger, B. Richmond, CHARLES Chesnut (1990)
Intermittent cyclical etidronate treatment of postmenopausal osteoporosis.The New England journal of medicine, 323 2
-
S. Ott, C. Chesnut (1989)
Calcitriol treatment is not effective in postmenopausal osteoporosis.Annals of internal medicine, 110 4
-
J. Wagner, T. Clarkson, R Clair, D. Schwenke, C. Shively, M. Adams (1991)
Estrogen and progesterone replacement therapy reduces low density lipoprotein accumulation in the coronary arteries of surgically postmenopausal cynomolgus monkeys.The Journal of clinical investigation, 88 6
-
D. Slovik, R. Neer, J. Potts (1981)
Short-term effects of synthetic human parathyroid hormone-(1--34) administration on bone mineral metabolism in osteoporotic patients.The Journal of clinical investigation, 68 5
-
J. Reeve, P. Meunier, J. Parsons, M. Bernat, O. Bijvoet, P. Courpron, C. Edouard, L. Klenerman, R. Neer, J. Renier, D. Slovik, F. Vismans, J. Potts (1980)
Anabolic effect of human parathyroid hormone fragment on trabecular bone in involutional osteoporosis: a multicentre trial.British Medical Journal, 280
-
L. Melton, S. Kan, H. Wahner, B. Riggs (1988)
Lifetime fracture risk: an approach to hip fracture risk assessment based on bone mineral density and age.Journal of clinical epidemiology, 41 10
-
W. Hayes, S. Piazza, P. Zysset (1991)
Biomechanics of fracture risk prediction of the hip and spine by quantitative computed tomography.Radiologic clinics of North America, 29 1
-
H. Genant, C. Cann, B. Ettinger, G. Gordan (1982)
Quantitative Computed Tomography of Vertebral Spongiosa: A Sensitive Method for Detecting Early Bone Loss After OophorectomyClinical Orthopaedics and Related Research, &NA;
-
M. Haarbo, M. Hassager, M. Jensen, M. Riis, M. Christiansen (1991)
Serum lipids, lipoproteins, and apolipoproteins during postmenopausal estrogen replacement therapy combined with either 19-nortestosterone derivatives or 17-hydroxyprogesterone derivativesThe American Journal of Medicine, 90
-
A. Parfitt, J. Gallagher, R. Heaney, C. Johnston, R. Neer, G. Whedon (1982)
Vitamin D and bone health in the elderly.The American journal of clinical nutrition, 36 5 Suppl
-
M. Chapuy, P. Chapuy, P. Meunier (1987)
Calcium and vitamin D supplements: effects on calcium metabolism in elderly people.The American journal of clinical nutrition, 46 2
-
W. Ray (1991)
Thiazide diuretics and osteoporosis: time for a clinical trial?Annals of internal medicine, 115 1
-
N. Mamelle, P. Meunier, P. Netter (1990)
Fluoride and vertebral fracturesThe Lancet, 336
-
M. Stampfer, G. Colditz, W. Willett, J. Manson, B. Rosner, F. Speizer, C. Hennekens (1991)
Postmenopausal estrogen therapy and cardiovascular disease. Ten-year follow-up from the nurses' health study.The New England journal of medicine, 325 11
-
R. Lindsay, J. Aitken, L. Anderson, D. Hart, E. Macdonald, A. Clarke (1976)
LONG-TERM PREVENTION OF POSTMENOPAUSAL OSTEOPOROSIS BY ŒSTROGEN EVIDENCE FOR AN INCREASED BONE MASS AFTER DELAYED ONSET OF ŒSTROGEN TREATMENTThe Lancet, 307
-
E. Georgiou, K. Ntalles, A. Papageorgiou, A. Korkotsidis, C. Proukakis (1989)
Bone mineral loss related to menstrual history.Acta orthopaedica Scandinavica, 60 2
-
J. Reginster (1991)
Effect of calcitonin on bone mass and fracture rates.The American journal of medicine, 91 5B
-
R. Eastell, A. Yergey, N. Vieira, S. Cedel, Rajiv Kumar, B. Riggs (1991)
Interrelationship among vitamin D metabolism, true calcium absorption, parathyroid function, and age in women: Evidence of an age‐related intestinal resistance to 1,25‐dihydroxyvitamin D actionJournal of Bone and Mineral Research, 6
-
R. Duda, J. O'brien, J. Katzmann, J. Peterson, K. Mann, B. Riggs (1988)
Concurrent assays of circulating bone Gla-protein and bone alkaline phosphatase: effects of sex, age, and metabolic bone disease.The Journal of clinical endocrinology and metabolism, 66 5
-
M. Tilyard, G. Spears, Janet Thomson, S. Dovey (1992)
Treatment of postmenopausal osteoporosis with calcitriol or calcium.The New England journal of medicine, 326 6
-
M. ansen, Kirsten vergaard, Bente JTRs, C. Christiansen (1991)
Role of peak bone mass and bone loss in postmenopausal osteoporosis: 12 year study.British Medical Journal, 303
-
B. Hulka (1990)
Hormone‐replacement therapy and the risk of breast cancerCA: A Cancer Journal for Clinicians, 40
-
D. Carter, G. Beaupré (1990)
Effects of fluoride treatment on bone strengthJournal of Bone and Mineral Research, 5
-
D. Baran, A. Sorensen, Joyce Grimes, R. Lew, A. Karellas, B. Johnson, J. Roche (1990)
Dietary modification with dairy products for preventing vertebral bone loss in premenopausal women: a three-year prospective study.The Journal of clinical endocrinology and metabolism, 70 1
-
P. Lips, J. Netelenbos, M. Jongen, F. Ginkel, A. Althuis, C. Schaik, W. Vijgh, J. Vermeiden, C. Meer (1982)
Histomorphometric profile and vitamin D status in patients with femoral neck fracture.Metabolic bone disease & related research, 4 2
-
Charles Pak, K. Sakhaee, J. Zerwekh, Carol Parcel, R. Peterson, Kenneth Johnson (1989)
Safe and effective treatment of osteoporosis with intermittent slow release sodium fluoride: augmentation of vertebral bone mass and inhibition of fractures.The Journal of clinical endocrinology and metabolism, 68 1
-
B. Riggs, K. Nelson (1985)
Effect of long term treatment with calcitriol on calcium absorption and mineral metabolism in postmenopausal osteoporosis.The Journal of clinical endocrinology and metabolism, 61 3
-
J. Bullamore, R. Wilkinson, J. Gallagher, B. Nordin, D. Marshall (1970)
Effect of age on calcium absorption.Lancet, 2 7672
-
J. Williams, M. Adams, H. Klopfenstein (1990)
Estrogen modulates responses of atherosclerotic coronary arteries.Circulation, 81 5
-
J. Gallagher, B. Riggs (1990)
Action of 1,25-dihydroxyvitamin D3 on calcium balance and bone turnover and its effect on vertebral fracture rate.Metabolism: clinical and experimental, 39 4 Suppl 1
-
J. Reginster, A. Albert, M. Lecart, P. Lambelin, D. Denis, R. Deroisy, M. Fontaine, P. Franchimont (1987)
1-YEAR CONTROLLED RANDOMISED TRIAL OF PREVENTION OF EARLY POSTMENOPAUSAL BONE LOSS BY INTRANASAL CALCITONINThe Lancet, 330
-
Masahiko Sato, W. Grasser, N. Endo, R. Akins, H. Simmons, D. Thompson, E. Golub, G. Rodan (1991)
Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure.The Journal of clinical investigation, 88 6
-
E. Barrett-Connor (1991)
Postmenopausal estrogen and prevention bias.Annals of internal medicine, 115 6
-
N. Weiss, C. Ure, J. Ballard, A. Williams, J. Daling (1980)
Decreased risk of fractures of the hip and lower forearm with postmenopausal use of estrogen.The New England journal of medicine, 303 21
-
M. Whitehead, P. Townsend, J. Pryse‐davies, T. Ryder, R. King (1981)
Effects of estrogens and progestins on the biochemistry and morphology of the postmenopausal endometrium.The New England journal of medicine, 305 27
-
B. Healy (1991)
The Yentl syndrome.The New England journal of medicine, 325 4
-
B. Hillner, J. Hollenberg, S. Pauker (1986)
Postmenopausal estrogens in prevention of osteoporosis. Benefit virtually without risk if cardiovascular effects are considered.The American journal of medicine, 80 6
-
Disease Prevention, R. Berg, J. Cassells (1990)
The Second Fifty Years: Promoting Health and Preventing Disability -
E. Canalis, M. Centrella, W. Burch, T. McCarthy (1989)
Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures.The Journal of clinical investigation, 83 1
-
R. Lindsay, A. Maclean, A. Kraszewski, D. Hart, A. Clark, J. Garwood (1978)
BONE RESPONSE TO TERMINATION OF ŒSTROGEN TREATMENTThe Lancet, 311
-
T. Key, M. Pike (1988)
The role of oestrogens and progestagens in the epidemiology and prevention of breast cancer.European journal of cancer & clinical oncology, 24 1
-
P. Elders, J. Netelenbos, P. Lips, F. Ginkel, Edwin Khoe, O. Leeuwenkamp, W. Hackeng, P. Stelt (1991)
Calcium supplementation reduces vertebral bone loss in perimenopausal women: a controlled trial in 248 women between 46 and 55 years of age.The Journal of clinical endocrinology and metabolism, 73 3
-
L. Bergkvist, H. Adami, I. Persson, R. Bergström, Brith Krusemo (1989)
PROGNOSIS AFTER BREAST CANCER DIAGNOSIS IN WOMEN EXPOSED TO ESTROGEN AND ESTROGEN-PROGESTOGEN REPLACEMENT THERAPYAmerican Journal of Epidemiology, 130
-
R. Heaney, R. Recker, P. Saville (1978)
Menopausal changes in bone remodeling.The Journal of laboratory and clinical medicine, 92 6
-
B. Riggs, S. Hodgson, W. O'fallon, E. Chao, H. Wahner, J. Muhs, S. Cedel, L. Melon (1990)
Effect of fluoride treatment on the fracture rate in postmenopausal women with osteoporosis.The New England journal of medicine, 322 12
-
E. Canalis, T. McCarthy, M. Centrella (1988)
Growth factors and the regulation of bone remodeling.The Journal of clinical investigation, 81 2
-
I. Reid, C. Alexander, A. King, H. Ibbertson (1988)
PREVENTION OF STEROID-INDUCED OSTEOPOROSIS WITH (3-AMINO-1-HYDROXYPROPYLIDENE)-1, 1-BISPHOSPHONATE (APD)The Lancet, 331
-
J. Aloia, Ashok Vaswani, James Yeh, K. Ellis, Seiichi Yasumura, S. Cohn (1988)
Calcitriol in the treatment of postmenopausal osteoporosis.The American journal of medicine, 84 3 Pt 1
-
V. Matkovic, D. Fontana, C. Tominac, P. Goel, C. Chesnut (1990)
Factors that influence peak bone mass formation: a study of calcium balance and the inheritance of bone mass in adolescent females.The American journal of clinical nutrition, 52 5
-
E. Eriksen, D. Colvard, N. Berg, M. Graham, K. Mann, T. Spelsberg, B. Riggs (1988)
Evidence of estrogen receptors in normal human osteoblast-like cellsScience, 241
-
D. Uebelhart, E. Gineyts, M. Chapuy, P. Delmas (1990)
Urinary excretion of pyridinium crosslinks: a new marker of bone resorption in metabolic bone disease.Bone and mineral, 8 1
-
M. Quigley, P. Martin, A. Burnier, P. Brooks (1987)
Estrogen therapy arrests bone loss in elderly women.American journal of obstetrics and gynecology, 156 6
-
R. Lindsay, J. Tohme (1990)
Estrogen treatment of patients with established postmenopausal osteoporosisInternational Journal of Gynecology & Obstetrics, 34
-
R. Civitelli, S. Gonnelli, F. Zacchei, S. Bigazzi, A. Vattimo, Lv Avioli, C. Gennari (1988)
Bone turnover in postmenopausal osteoporosis. Effect of calcitonin treatment.The Journal of clinical investigation, 82 4
-
J. Gallagher, D. Goldgar, A. Moy (1987)
Total bone calcium in normal women: Effect of age and menopause statusJournal of Bone and Mineral Research, 2
-
T. Storm, G. Thamsborg, T. Steiniche, H. Genant, O. Sørensen (1990)
Effect of intermittent cyclical etidronate therapy on bone mass and fracture rate in women with postmenopausal osteoporosis.The New England journal of medicine, 322 18
-
MD Lufkin, MD Wahner, PhD O'Fallon, MD Hodgson, Mbbs Kotowicz, Mph Lane, MD Judd, MD Caplan, MD Riggs (1992)
Treatment of Postmenopausal Osteoporosis with Transdermal EstrogenAnnals of Internal Medicine, 117
-
A. Parfitt, C. Mathews, Villanueva Ar, Michael Kleerekoper, Boy Frame, D. Rao (1983)
Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss.The Journal of clinical investigation, 72 4
-
Sarita Dhuper, Michelle Warren, Jeanne Brooks-Gunn, R. Fox (1990)
Effects of hormonal status on bone density in adolescent girls.The Journal of clinical endocrinology and metabolism, 71 5
-
P. Delmas, J. Dupuis, F. Duboeuf, M. Chapuy, P. Meunier (1990)
Treatment of vertebral osteoporosis with disodium monofluorophosphate: Comparison with sodium fluorideJournal of Bone and Mineral Research, 5
-
B. Henderson (1989)
The cancer question: an overview of recent epidemiologic and retrospective data.American journal of obstetrics and gynecology, 161 6 Pt 2
-
J. Reginster, M. Lecart, R. Deroisy, N. Sarlet, D. Denis, D. Ethgen, J. Collette, P. Franchimont (1989)
PREVENTION OF POSTMENOPAUSAL BONE LOSS BY TILUDRONATEThe Lancet, 334
-
G. Dalsky, K. Stocke, A. Ehsani, E. Slatopolsky, Waldon Lee, S. Birge (1988)
Weight-bearing exercise training and lumbar bone mineral content in postmenopausal women.Annals of internal medicine, 108 6
-
D. Dempster, E. Shane, W. Horbert, R. Lindsay (1986)
A simple method for correlative light and scanning electron microscopy of human iliac crest bone biopsies: Qualitative observations in normal and osteoporotic subjectsJournal of Bone and Mineral Research, 1
-
R. Heaney (1991)
Effect of calcium on skeletal development, bone loss, and risk of fractures.The American journal of medicine, 91 5B
-
S. Cummings, D. Bates, D. Black (1991)
CLINICAL USE OF BONE DENSITOMETRYThe New England Journal of Medicine, 324
-
B. Dawson-Hughes, G. Dallal, E. Krall, Laura Sadowski, N. Sahyoun, S. Tannenbaum (1990)
A controlled trial of the effect of calcium supplementation on bone density in postmenopausal women.The New England Journal of Medicine, 323
-
R. Prince, Margaret Smith, I. Dick, R. Price, P. Webb, N. Henderson, M. Harris (1991)
Prevention of postmenopausal osteoporosis. A comparative study of exercise, calcium supplementation, and hormone-replacement therapy.The New England journal of medicine, 325 17
- Publisher
- The New England Journal of Medicine
- ISSN
- 0028-4793
- eISSN
- 1533-4406
- DOI
- 10.1056/NEJM199208273270908
- pmid
- 1640955
- Publisher site
- See Article on Publisher Site
Abstract
OSTEOPOROSIS is one of the most important disorders associated with aging.1,2 More than 1.5 million Americans have fractures related to osteoporosis each year, with attendant pain, deformity, and loss of independence. The annual cost to the U.S. health care system is at least $10 billion.1,2 Because of the aging of the population and increases over time in the incidence of fractures, these already huge costs will more than double over the next 30 years3 unless a comprehensive program of prevention and treatment is initiated soon. The most important preventable cause of fractures is low bone mass. During the course of . . .
Journal
The New England Journal of Medicine – The New England Journal of Medicine
Published: Aug 27, 1992