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Ventral medullary extracellular fluid pH and PCO2 during hypoxemia

Ventral medullary extracellular fluid pH and PCO2 during hypoxemia JAVAHERI,SHAHROKH,AND Luc J. TEPPEMA. VentraZmedullary extracellular fluid pH and PCO, during hypoxemia. J. Appl. Physiol. 63(4): 1567-4571, 1987.-We designed experiments to study changes in ventral medullary extracellular fluid (ECF) Pco2 and pH during hypoxemia. Measurements were spontaneously chloralose-urethan-anesthetized made in chemodenervation. breathing cats (n = 12) with peripherial Steady-state measurements were made during normoxemia [arterial PO2 (Pao,) = 106 Torr], hypoxemia (Pao, = 46 Torr), and recovery ( Pao, = PO5 Torr), with relatively constant arterial Pcoz (-44 Torr). Mean values of ventilation were 945,6$3, and 1,037 ml/min during normoxemia, hypoxemia, and recovery from hypoxemia, respectively. occurred in each cat during hypoxemia. Mean values of medullary ECF Pco2 were 57.7 t 7.2 (SD), 59.4 $- 9.7, and 57.4 k 7.2 Torr during normoxemia, hypoxemia, and recovery to normoxemia, respectively; respective values for ECF [H’] were 60.9 t 8.0, 64.4 & 11.6, and 62.9 t 9.2 neq/l. Mean values of calculated ECF [HCO;] were 22.8 & 3.0, 21.7 t 3.3, and 21.4 t 3.1 meq/l during normoxemia, hypoxemia, and recovery, respectively. Changes in medullary ECF PCO~ and [H’] were not statistically significant. Therefore hypoxemia caused independent of changes in ECF acid-base variables. Furthermore, on return to normoxemia, ventilation rose http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Applied Physiology The American Physiological Society

Ventral medullary extracellular fluid pH and PCO2 during hypoxemia

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Publisher
The American Physiological Society
Copyright
Copyright © 1987 the American Physiological Society
ISSN
8750-7587
eISSN
1522-1601
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Abstract

JAVAHERI,SHAHROKH,AND Luc J. TEPPEMA. VentraZmedullary extracellular fluid pH and PCO, during hypoxemia. J. Appl. Physiol. 63(4): 1567-4571, 1987.-We designed experiments to study changes in ventral medullary extracellular fluid (ECF) Pco2 and pH during hypoxemia. Measurements were spontaneously chloralose-urethan-anesthetized made in chemodenervation. breathing cats (n = 12) with peripherial Steady-state measurements were made during normoxemia [arterial PO2 (Pao,) = 106 Torr], hypoxemia (Pao, = 46 Torr), and recovery ( Pao, = PO5 Torr), with relatively constant arterial Pcoz (-44 Torr). Mean values of ventilation were 945,6$3, and 1,037 ml/min during normoxemia, hypoxemia, and recovery from hypoxemia, respectively. occurred in each cat during hypoxemia. Mean values of medullary ECF Pco2 were 57.7 t 7.2 (SD), 59.4 $- 9.7, and 57.4 k 7.2 Torr during normoxemia, hypoxemia, and recovery to normoxemia, respectively; respective values for ECF [H’] were 60.9 t 8.0, 64.4 & 11.6, and 62.9 t 9.2 neq/l. Mean values of calculated ECF [HCO;] were 22.8 & 3.0, 21.7 t 3.3, and 21.4 t 3.1 meq/l during normoxemia, hypoxemia, and recovery, respectively. Changes in medullary ECF PCO~ and [H’] were not statistically significant. Therefore hypoxemia caused independent of changes in ECF acid-base variables. Furthermore, on return to normoxemia, ventilation rose

Journal

Journal of Applied Physiology – The American Physiological Society

Published: Oct 1, 1987

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