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Substrate and hormonal responses to exercise in women using oral contraceptives

IT IS NOW WELL-KNOWN that sex steroids are markedly creased durg , particularly durg the luteal of the menstrual cycle (6, 8, 25). Comparisons of hmones the follicular luteal of nmal, fasted, glucose-fed women dicate that the metabolic responses to depend on the nutritional status the of the menstrual cycle when ovarian steroid hmone concentrations are creased (6). This suggests that the ovarian steroids might fluence substrate metabolism, because estrogens can crease glycogen stage mouse skeletal muscle liver (1). s (OC) conta potent synthetic steroids.deed, their chronic use over several years can crease sul resistance women (44). OC use also creases cholesterol triglycerides but seems not to affect free fatty acid (FFA) turnover at rest (23). Animal studies have also shown that admistration of estrogens progesterone creases hepatic gluconeogenesis (30). skeletal muscle of ovariectomized rats estrogen treatment stimulated FFA oxidation hibited glucose oxidation at rest durg (24). The effects of OC use on hmonal substrate responses to have not been determed. However, given the fact that there can be differences metabolic responses between the follicular luteal s durg nmally menstruatg women when steroid levels are low high, respectively (7), the presence of synthetic steroids OC preparations may have http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Applied Physiology The American Physiological Society

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