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secretion in conscious rats SMI CHOI-KWON, RICHARD MCCARTY, ALEX J. BAERTSCHI Departments of Physiology Psychology, University of Virginia School of Medicine, Charlottesville, Virginia 22908 liver. In fact, with the use of topical superfusion of various structures, it was shown that osmo are localized in the area of the portal vein 1990.-Saline solutions (NaCl, 2 ml, pH 7.4, lo-598 mosmol/ mesenteric vessels draining the upper small intestine (4, kgHzO) were infused over 4 min in conscious rats, via tail artery 6,30) project via spinal afferents onto magnocellular catheter or intra tube. Intra s of hyperhypothalamic neurons (31). hypotonic solutions caused, within 14.4 t 2.2 min, a Doubts persisted about the physiological involvement maximal increase decrease, respectively, of plasma vasoof osmo because nonphysiological pressin (AVP) relative to time controls (r = 0.97; P < 0.00001) methods of osmostimulation were applied or anesthesia without affecting plasma osmolality (r = -0.09; P c was used, resulting in supraphysiological base lines (400.92). Mean changes of plasma AVP between 11 21 min were also correlated with the osmolality of (r 60 pg/ml) of plasma AVP. Furthermore, several reports = 0.72; P < O.OOOOOl), whereas osmolality was unfailed to provide evidence for a osmoreceptor changed
AJP - Endocrinology and Metabolism – The American Physiological Society
Published: Jul 1, 1990
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