, HERMES A., ENOCH P. WEI, A. JARRELL RAPER, WILLIAM I. ROSENBLUM,RUDOLPH M. NAVARI, ANDJOHN L. PATTERSON, JR. Role of tissue in local of cerebral microcirculation. Am. J. Physiol. 234(5):H582-H591, Experiments were carried out in 115 cats of either sex, weighing between 2 and 4 kg. Eighty-two animals were anesthetized with intravenous sodium pentobarbital (30 mg/kg). The other 33 animals were anesthetized with intravenous urethan (60 mg/kg). The animals anesthetized with urethan were used in experiments in which convulsions were induced, because Metrazole (pentylenetetrazole) did not induce seizures in theâpentobarbital-anesthetized cats. ARer completion of tracheostomy, each animal was ventilated with a positivepressure respirator and received 0.4 mg/kg of decamearterioles; vasodilator metabolites; &hernia; vasodilation; thonium bromide âintravenously for skeletal muscle pametabolic of blood flow; fluorocarbon ralysis. The end-expiratory CO, of the animal was continuously monitored with a Beckman infrared CO, analyzer and maintained at a constant level of about 35 ONE OF THE POPULAR THEORIES for local Of mmHg throughout each experiment by adjusting the blood flow is based on the premise that alterations in respirator rate and volume. Arterial blood pressure was blood pressure or changes in metabolism induce changes measured with a Statham P23Db pressure transducer in
AJP - Heart and Circulatory Physiology – The American Physiological Society
Published: May 1, 1978
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