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University ALBERT of Tennessee Center for the Health Sciences, HIROKO, LDA G. ALBERT . to hemorrhage hypotension the toad Opsanustau. Am. J. Physiol. 237(2): HlO&Hlll, 1979 or Am. J. Physiol.: Heart Circ. Physiol. 6(2): H105-Hlll, 1979.-Renal the juxt cells evolved primitive bony es, whereas the macula densa emerged later vertebrate phylogeny. We attempted to determe whether a renal arteriolar baroreceptor exists the toad Opsanustau, which possess granulated cells the kidneys, but lack glomeruli macula densa. Cumulative hemorrhage of 1.5, 3, 6, 12, 18 ml/kg, or a sgle massive bleedg from unanesthetized toad, kept 50% seawater, caused an immediate significant decrease mean aortic pressure stepwise creases (5-20 times) of plasma activity (PRA). Papavere (10 mg/kg) caused hypotension creased PRA. Moxidil (6-12 mg/kg) neither decreased blood pressure nor creased PRA. The results suggest that toad respond to hemorrhage acute hypotension with release despite the absence of a macula densa. It remas to be determed whether decreased renal perfusion pressure due to decreased dorsal aortic pressure stimulated the receptor the granulated cells or whether the renal nerves may be volved. release; KIDNEYS teleost; plasma clear. Thus we tended to defe the present study whether the renal arteriolar baroreceptor exists the toad
AJP - Heart and Circulatory Physiology – The American Physiological Society
Published: Aug 1, 1979
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