Departments of Movement Sciences, Physiology, Anatomy/Embryology, University of Limburg, 6200 MD Maastricht, The Netherls VERMEULEN, J.H.,H. KUIPERS,J. DRUKKER.R~- as to the amount lationship between in rats. J. Appl. Physiol. 71(3): 999-1004, 1991.-The Biomedical Center, relationship beween the amount of the of creatine kinase (CK), aspartate aminotransferase(AST), lactate dehydrogenase (LD) wasstudied. Gender differencesin histological were also studied. Serial pre- postexerciseblood samples were drawn from untrained male female catheterized Wistar rats that ran 1.5 or 2.5 h on a treadmill (incline loo). Three days postexercise, was quantified morphometrically in five different hindlimb forearm s. The 1.5 2.5 h of exercise elicited histological only in the soleus.Significant plasmaCK, AST, LD elevations were found immediately postexerciseboth in male female rats. However, the was significantly greater in malesthan in females.Part of this could be explained by differences in clearance rates between . No gender difference in amount of histological was found. The actual volume of histological was significantly lessthan the calculated basedon .An increasein the exerciseduration from 1.5 to 2.5 h resulted in a disproportional increasein both histological .From the present study it is concluded that is not clearly reflected in histological . creatine kinase; aspartate aminotransferase; inflammation; lactate dehydrogenase;morphometry; gender differences; soleus
Journal of Applied Physiology – The American Physiological Society
Published: Sep 1, 1991
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