J. A. ROMIJN, E. F. COYLE, L. S. SIDOSSIS, A. GASTALDELLI, J. F. HOROWITZ, E. ENDERT, AND R. R. WOLFE Metabolism Unit, Shriners Burns Institute and Departments of Anesthesiology and of Surgery, University of Texas Medical Branch, Galveston 77550; Human Performance Laboratory, Department of Kinesiology and Health, The University of Texas at Austin, Austin, Texas 78712; and Department of Endocrinology, Academisch Medisch Centrum, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands Romijn, J. A., E. F. Coyle, L. S. Sidossis, A. Gastaldelli, J. F. Horowitz, E. Endert, and R. R. Wolfe. Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration. Am. J. Physiol. 265 (Endocrinol. Metczb. 28): E380-E391, 199X-Stable isotope tracers and indirect calorimetry were usedto evaluate the regulation of endogenous and glucosemetabolismin relation to fat exerciseintensity and duration. Five trained subjectswerestudied during exercise intensities of 25, 65, and 85% of maximal oxygen consumption (VO 2max). Plasma glucosetissue uptake and muscleglycogen oxidation increasedin relation to exercise intensity. In contrast, peripheraipolysis was stimulated maximally at the lowest exercise intensity, and fatty acid release into plasmadecreased with increasingexercise intensity. Muscle triglyceride lipolysis was stimulated only at higher intensities. During 2 h of exercise at 65%
AJP - Endocrinology and Metabolism – The American Physiological Society
Published: Sep 1, 1993
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