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Rat lung metabolism after 3 days of continuous exposure to 0.6 ppm ozone

Rat lung metabolism after 3 days of continuous exposure to 0.6 ppm ozone AJP - Endocrinology and publishes results of original studies about endocrine and metabolic systems on any level of organization. It is published 12 times a year (monthly) by the American Physiological Society, 9650 Rockville Pike, Bethesda MD 20814-3991. Copyright © 1986 by the American Physiological Society. ISSN: 0193-1849, ESSN: 1522-1555. Visit our website at http://www.the-aps.org/. DAVID J. P. BASSETT AND ELIZABETH BOWEN-KELLY Department of Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland 21205 BASSETT, DAVID J. P., AND ELIZABETH BOWEN-KELLY. Rat 3 days of continuous exposure to 0.6 ppm ozone. Am. J. Physiol. 250 (Endocrinol. Metab. 13): E131E136, 1986.-Continuous exposure of rats to low concentrations of ozone has previously been associated with enhanced metabolic enzyme activities, when measured in homogenates. In this study, metabolic rates were measured in intact perfused s with altered pathology brought about by 3 days continuous exposure to 0.6 ppm ozone. Increased of ozone-exposed s was indicated by a twofold enhancement in glucose utilization, associated with a 62% increase in lactate formation and a 166% increase in the rate of 14C0, production from D-[U-14C]glucose from control values of 5.2 t 0.5 pm01 lactate and 4.4 * 0.6 pmol http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png AJP - Endocrinology and Metabolism The American Physiological Society

Rat lung metabolism after 3 days of continuous exposure to 0.6 ppm ozone

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Publisher
The American Physiological Society
Copyright
Copyright © 1986 the American Physiological Society
ISSN
0193-1849
eISSN
1522-1555
Publisher site
See Article on Publisher Site

Abstract

AJP - Endocrinology and publishes results of original studies about endocrine and metabolic systems on any level of organization. It is published 12 times a year (monthly) by the American Physiological Society, 9650 Rockville Pike, Bethesda MD 20814-3991. Copyright © 1986 by the American Physiological Society. ISSN: 0193-1849, ESSN: 1522-1555. Visit our website at http://www.the-aps.org/. DAVID J. P. BASSETT AND ELIZABETH BOWEN-KELLY Department of Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland 21205 BASSETT, DAVID J. P., AND ELIZABETH BOWEN-KELLY. Rat 3 days of continuous exposure to 0.6 ppm ozone. Am. J. Physiol. 250 (Endocrinol. Metab. 13): E131E136, 1986.-Continuous exposure of rats to low concentrations of ozone has previously been associated with enhanced metabolic enzyme activities, when measured in homogenates. In this study, metabolic rates were measured in intact perfused s with altered pathology brought about by 3 days continuous exposure to 0.6 ppm ozone. Increased of ozone-exposed s was indicated by a twofold enhancement in glucose utilization, associated with a 62% increase in lactate formation and a 166% increase in the rate of 14C0, production from D-[U-14C]glucose from control values of 5.2 t 0.5 pm01 lactate and 4.4 * 0.6 pmol

Journal

AJP - Endocrinology and MetabolismThe American Physiological Society

Published: Feb 1, 1986

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