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Paced breathing and phrenic nerve responses evoked by epidural stimulation following complete high cervical spinal cord injury in rats

Paced breathing and phrenic nerve responses evoked by epidural stimulation following complete... The present work offers the first demonstration of successful life-supporting breathing paced by epidural stimulation (EDS) at the level of the phrenic nucleus, following a complete spinal cord injury in unanesthetized, decerebrate rats. Moreover, our experiments showed time- and frequency-dependent changes of evoked phrenic nerve activity during EDS that may serve as a target mechanism for pacing spinal phrenic motor networks. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Applied Physiology The American Physiological Society

Paced breathing and phrenic nerve responses evoked by epidural stimulation following complete high cervical spinal cord injury in rats

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ISSN
8750-7587
eISSN
1522-1601
DOI
10.1152/japplphysiol.00895.2017
Publisher site
See Article on Publisher Site

Abstract

The present work offers the first demonstration of successful life-supporting breathing paced by epidural stimulation (EDS) at the level of the phrenic nucleus, following a complete spinal cord injury in unanesthetized, decerebrate rats. Moreover, our experiments showed time- and frequency-dependent changes of evoked phrenic nerve activity during EDS that may serve as a target mechanism for pacing spinal phrenic motor networks.

Journal

Journal of Applied Physiology – The American Physiological Society

Published: Sep 1, 2018

References

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