Mechanism of insulin action on glucose transport in rat skeletal muscle

Mechanism of insulin action on glucose transport in rat skeletal muscle University BARNARD, of California, AND hs GLEN Department Angeles, California K. GRIMDITCH 90024 Materials. The materials used for the isolation procedure were the same as described previously (11). The purified porcine insulin was donated by Eli Lilly (Indianapolis, IN). Cytochalasin B was obtained from Aldrich Chemical. The tracers, D- [3H], L- [ 14C], D[Wlmannitol, and [3H]cytochalasin B with specific activities of 33.1 Ci/mol, 47.0 mCi/mmol, 48.7 mCi/mmol, and 18.5 Ci/mmol, respectively, were purchased from kinetics; cytochalasin B; sarcolemmal New England Nuclear (Boston, MA). All other chemicals were obtained from Sigma Chemical. Animals. Female Sprague-Dawley rats were purchased SKELETAL MUSCLE is a major tissue for blood from Charles River Laboratories (Wilmington, MA) and utilization and a primary target tissue for insulin action. weighed -250 g at the time of death. Standard rat chow The mechanism by which insulin acts to increase and water were provided ad libitum to all rats. Unless in this important tissue is unknown. Several otherwise stated, n refers to the number of SL preparamodels have been used to examine the mechanism of tions per group. insulin action. To date, studies examining uptake SL isolation. Skeletal muscle SL were prepared in skeletal muscle have primarily used http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png AJP - Endocrinology and Metabolism The American Physiological Society

Mechanism of insulin action on glucose transport in rat skeletal muscle

Loading next page...
 
/lp/the-american-physiological-society/mechanism-of-insulin-action-on-glucose-transport-in-rat-skeletal-EWD0AAfE6b
Publisher
The American Physiological Society
Copyright
Copyright © 1988 the American Physiological Society
ISSN
0193-1849
eISSN
1522-1555
Publisher site
See Article on Publisher Site

Abstract

University BARNARD, of California, AND hs GLEN Department Angeles, California K. GRIMDITCH 90024 Materials. The materials used for the isolation procedure were the same as described previously (11). The purified porcine insulin was donated by Eli Lilly (Indianapolis, IN). Cytochalasin B was obtained from Aldrich Chemical. The tracers, D- [3H], L- [ 14C], D[Wlmannitol, and [3H]cytochalasin B with specific activities of 33.1 Ci/mol, 47.0 mCi/mmol, 48.7 mCi/mmol, and 18.5 Ci/mmol, respectively, were purchased from kinetics; cytochalasin B; sarcolemmal New England Nuclear (Boston, MA). All other chemicals were obtained from Sigma Chemical. Animals. Female Sprague-Dawley rats were purchased SKELETAL MUSCLE is a major tissue for blood from Charles River Laboratories (Wilmington, MA) and utilization and a primary target tissue for insulin action. weighed -250 g at the time of death. Standard rat chow The mechanism by which insulin acts to increase and water were provided ad libitum to all rats. Unless in this important tissue is unknown. Several otherwise stated, n refers to the number of SL preparamodels have been used to examine the mechanism of tions per group. insulin action. To date, studies examining uptake SL isolation. Skeletal muscle SL were prepared in skeletal muscle have primarily used

Journal

AJP - Endocrinology and MetabolismThe American Physiological Society

Published: May 1, 1988

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create folders to
organize your research

Export folders, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off