Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Ileal transposition into the upper jejunum affects lipid and bile salt absorption in rats

Ileal transposition into the upper jejunum affects lipid and bile salt absorption in rats affects AND PATRICK State University TSO Medical Center, ADAPTATION after either intestinal resection or transposition of one region of gut to another has been previously reported (8, 11,22). Jejunectomy (12,22,29, 43) and ileojejunal transposition (1, 12, 21, 28, 36, 39) have both been reported to produce mucosal hyperplasia. It was recently reported that transposition of the ileum to the site of the jejunum produces increases in the mucosal mass of the entire bowel (i.e., duodenum and jejunum, as well as ileum) (38). The mechanism responsible for the hyperplasia is not clear, but factors such as luminal nutrients, pancreaticobiliary secretions, and hormones are believed to be involved (11). The functional consequences of such mucosal hyperplasia have not been clearly defined. Few studies have examined whether mucosal hyperplasia of the small intestine after ileal transposition is associated with altered ability to absorb nutrients. INTESTINAL 0193-1857/96 $5.00 Copyright Gleeson et al. (20) showed an increase in glucose absorption by a segment of hyperplastic transposed ileum, whereas the segment of jejunum that had been displaced distally showed impaired glucose absorption. Other studies have shown increases in sucrase specific activity in ileal tissue after ileal transposition (28, 40, 41). These studies have examined http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png AJP - Gastrointestinal and Liver Physiology The American Physiological Society

Ileal transposition into the upper jejunum affects lipid and bile salt absorption in rats

Download PDF
11 pages

Loading next page...
 
/lp/the-american-physiological-society/ileal-transposition-into-the-upper-jejunum-affects-lipid-and-bile-salt-SzjSqCGhnd

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
The American Physiological Society
Copyright
Copyright © 1996 the American Physiological Society
ISSN
0193-1857
eISSN
1522-1547
Publisher site
See Article on Publisher Site

Abstract

affects AND PATRICK State University TSO Medical Center, ADAPTATION after either intestinal resection or transposition of one region of gut to another has been previously reported (8, 11,22). Jejunectomy (12,22,29, 43) and ileojejunal transposition (1, 12, 21, 28, 36, 39) have both been reported to produce mucosal hyperplasia. It was recently reported that transposition of the ileum to the site of the jejunum produces increases in the mucosal mass of the entire bowel (i.e., duodenum and jejunum, as well as ileum) (38). The mechanism responsible for the hyperplasia is not clear, but factors such as luminal nutrients, pancreaticobiliary secretions, and hormones are believed to be involved (11). The functional consequences of such mucosal hyperplasia have not been clearly defined. Few studies have examined whether mucosal hyperplasia of the small intestine after ileal transposition is associated with altered ability to absorb nutrients. INTESTINAL 0193-1857/96 $5.00 Copyright Gleeson et al. (20) showed an increase in glucose absorption by a segment of hyperplastic transposed ileum, whereas the segment of jejunum that had been displaced distally showed impaired glucose absorption. Other studies have shown increases in sucrase specific activity in ileal tissue after ileal transposition (28, 40, 41). These studies have examined

Journal

AJP - Gastrointestinal and Liver Physiology – The American Physiological Society

Published: Oct 1, 1996

There are no references for this article.