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JOSEPHE P. BRIGGS FRED S. WRIGHT Department of Physiology, Yale University School of Medice, New Haven, Veterans Admistration Hospital, West Haven, Connecticut 06516 Connecticut 06510, BRIGGS, JOSEPHE P., FRED S. WRIGHT. of glomerular filtration rate: site of the . Am. J. Physiol. 236(l): F40-F47, 1979 or Am. J. Physiol.: Renal Fluid Electrolyte Physiol. 5(l): F40-F47, 1979. -To determe whether the changes sgle nephron vascular resistance that follow creased rates of flow through the loop of Henle of the same nephron occur at a pre- or a postglomerular site, it is necessary to measure the effect of creased loop flow on sgle nephron filtration fraction ( SNFF). Anatomical criteria were developed to identify surface stellate vessels proximal tubule segments belongg to the same nephron. The criteria were verified by demonstratg that the usual crease hematocrit (Hct) between systemic artery stellate vessel could be prevented by placement of an immobile block the associated proximal tubule. Stellate vessel pressure (P&, stop-flow pressure (P& tubule fluid flow rate, tubule fluid ul concentration, stellate vessel Hct were measured vascular or tubular segments, while the loop of Henle of the same sgle nephron was perfused alternately at normal high rates. Values were calculated for
AJP - Renal Physiology – The American Physiological Society
Published: Jan 1, 1979
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