METHODS AND CO-WORKERS (21) have demonstrated that small ve pressure of laterally recumbent pony (-30 mmHg) is over twice that measured analogous tissues or species (e.g., humans or dogs; -12 mmHg (1, 3, 15). Because small ve pressure represents lower limit for capillary pressure, y suggested that substantial capillary fluid filtration should occur across al microvasculature, unless adjustments occur or Starlg , lymph flow, and/or capillary filtration coefficient, to limit possible edemagenic effects of high capillary pressure (21). a subsequent study (ll), al capillary pressure was estimated to be 34 mmHg by step flow method (18). Measurements of capillary pressure dog forelimb averaged only 15 mmHg (3, 11). Assumg or Starlg are similar two species, high capillary pressure eque should be associated with a substantial efflux of fluid from vascular to extravascular compartment. However, impact of this relatively high capillary pressure on dynamics of microvascular fluid exchange eque remas to be determed. To this end, ROBSON 1580 0161-7567/88 $1.50 Surgical procedure. Experiments were performed on six healthy adult horses (350-500 kg body wt) itially anestized with sodium thiamylal(3 mg/kg) and mataed a state of anessia with pentobarbital sodium. horses were placed lateral recumbency, tubated with a cuffed endotracheal
Journal of Applied Physiology – The American Physiological Society
Published: Apr 1, 1988
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