in rats running J. A. SCHWANE AND R. B. ARMSTRONG Departme of Physiology, Oral Roberts University School of Medicine, Tulsa, Oklahoma SCHWANE, J. A., AND R. B. ARMSTRONG. Effect of training on skeletal injury from downhill running in rats. J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 55(3): 969-975, 1983.-Experimes were conducted to test the hypothesis that injury to skeletal in rats resuing from prolonged downhill running is preveed to a greater exte by prior downhill training than by either uphill or level training. Changes in plasma creatine phosphokinase (CPK) activity and glucose-6phosphate dehydrogenase (G-6-PDase) activity in the soleus (S), vastus iermedius (VI), and medial head of triceps brachii (TM) s were evaluated as markers of injury 48 h after 90 min of iermitte downhill running (16 momin-â). Prior to this ace downhill run, groups of rats were trained by either downhill (-16â), level (Oâ), or uphill (+16O) running (16 m .min-â) for 30 min/day. Training duration was either 5 days or 1 day. A training effect (i.e., reduced injury) was indicated if G-6-PDase or plasma CPK activity in a trained group following the 90-min downhill run was not differe from that of nonexercised corol animals and/or if it
Journal of Applied Physiology – The American Physiological Society
Published: Sep 1, 1983
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