College of Medicine, University of Ariza, Tucs, Ariza , SHAR M., PAUL C. JOHNS. Effect of microcirculatory level. Informati of this nature would autoregulati in cat sartorius muscle. appear to be of fundamental importance in assessingthe Am. J. Physiol. 241 (Heart Circ. Physiol. 10): H807-H815, ctributi of metabolic factors to autoregulati. 1981.-To assess the role of O2 in autoregulati, The purpose of this study was to examine the possible arteriolar diameter erythrocyte velocity were measured in role of 02 in the autoregulatory respse. The isolated individual microvessels of the cat sartorius muscle while amautoperfused cat sartorius muscle was used. The respse bient 02 tensi (Po2) perfusi pressure were altered. The of arterioles to a decrease in perfusi pressure was muscle surface was covered with a layer of silice fluid equilexamined under cditis where tissue Paz was mainibrated with a gas mixture ctaining O-20% 02. Under ctrol tained at several different levels by increasing the Paz of cditis (0% 02) all except the largest arterioles dilated with fluid bathing the muscle surface. If autoregulati of pressure reducti, all showed significant autoregulati. Elevated POT diminished regulati dila is due primarily to 02 deficiency, the mainteti in large small arterioles when
AJP - Heart and Circulatory Physiology – The American Physiological Society
Published: Dec 1, 1981
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