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Effect of Hemorrhagic Shock on Certain Antibacterial Defense Mechanisms in the Rabbit

Effect of Hemorrhagic Shock on Certain Antibacterial Defense Mechanisms in the Rabbit Abstract Rabbits were subjected to hemorrhagic shock, then injected intravenously with bacteria during the posttransfusion period. Little if any loss of capacity to clear the blood stream of strains of either Staphylococcus aureus , coagulase positive, or Staph . albus , coagulase negative, was demonstrated. However, the rate at which bacterial clearance occurred was delayed. Plasma was obtained from rabbits subjected to lethal hemorrhagic shock, before hemorrhage and shortly after retransfusion. The antibacterial activity of the plasma against strains of Klebsiella pneumoniae , Escherichia freundii , and Staph . aureus was found to remain unchanged. However, the plasma from approximately one-third of the rabbits lost the capacity to kill or suppress a strain of Staph . albus. Submitted on June 29, 1956 Copyright © 1957 the American Physiological Society http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Applied Physiology The American Physiological Society

Effect of Hemorrhagic Shock on Certain Antibacterial Defense Mechanisms in the Rabbit

Journal of Applied Physiology , Volume 10 (1): 88 – Jan 1, 1957

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Publisher
The American Physiological Society
Copyright
Copyright © 1957 the American Physiological Society
ISSN
8750-7587
eISSN
1522-1601
Publisher site
See Article on Publisher Site

Abstract

Abstract Rabbits were subjected to hemorrhagic shock, then injected intravenously with bacteria during the posttransfusion period. Little if any loss of capacity to clear the blood stream of strains of either Staphylococcus aureus , coagulase positive, or Staph . albus , coagulase negative, was demonstrated. However, the rate at which bacterial clearance occurred was delayed. Plasma was obtained from rabbits subjected to lethal hemorrhagic shock, before hemorrhage and shortly after retransfusion. The antibacterial activity of the plasma against strains of Klebsiella pneumoniae , Escherichia freundii , and Staph . aureus was found to remain unchanged. However, the plasma from approximately one-third of the rabbits lost the capacity to kill or suppress a strain of Staph . albus. Submitted on June 29, 1956 Copyright © 1957 the American Physiological Society

Journal

Journal of Applied PhysiologyThe American Physiological Society

Published: Jan 1, 1957

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