Eccentric exercise-induced injury to rat skeletal muscle

Eccentric exercise-induced injury to rat skeletal muscle J. A. Oral Roberts University School of Medicine, R. B., fc. W. J. A. . to rat skeletal . J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 54( 1): 8093, 1983.-These experiments were designed to study skeletal pathology resulting from -biased exercise in rats. The effects on the s of running on a treadmill on a O incline (similar amounts of concentric contractions), down a 16’ incline (primarily contractions), up a 16’ incline (primarily concentric contractions) at 16 me min-l for 90 min were assessed by following postexercise changes in 1) plasma creatine kinase lactate dehydrogenase activities, 2) glucose-6-phosphate dehydrogenase (G-6-PDase) (bio- histochemically) in the physiological extensor s, 3) histological appearance of the s. The data indicate the following. 1) Whereas all exercise protocols resulted in elevations of plasma enzymes immediately after running, only exercise caused late phase elevations 1.5-2 days postexercise. 2) Significant increases in G-6PDase , which were always associated with accumulations of mononuclear cells, always occurred within some s of each extensor group l-3 days following downhill uphill running did not occur following level running; the increases in were usually of lower magnitude in the s of uphill runners than in those of downhill runners; the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Applied Physiology The American Physiological Society

Eccentric exercise-induced injury to rat skeletal muscle

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Publisher
The American Physiological Society
Copyright
Copyright © 1983 the American Physiological Society
ISSN
8750-7587
eISSN
1522-1601
Publisher site
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Abstract

J. A. Oral Roberts University School of Medicine, R. B., fc. W. J. A. . to rat skeletal . J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 54( 1): 8093, 1983.-These experiments were designed to study skeletal pathology resulting from -biased exercise in rats. The effects on the s of running on a treadmill on a O incline (similar amounts of concentric contractions), down a 16’ incline (primarily contractions), up a 16’ incline (primarily concentric contractions) at 16 me min-l for 90 min were assessed by following postexercise changes in 1) plasma creatine kinase lactate dehydrogenase activities, 2) glucose-6-phosphate dehydrogenase (G-6-PDase) (bio- histochemically) in the physiological extensor s, 3) histological appearance of the s. The data indicate the following. 1) Whereas all exercise protocols resulted in elevations of plasma enzymes immediately after running, only exercise caused late phase elevations 1.5-2 days postexercise. 2) Significant increases in G-6PDase , which were always associated with accumulations of mononuclear cells, always occurred within some s of each extensor group l-3 days following downhill uphill running did not occur following level running; the increases in were usually of lower magnitude in the s of uphill runners than in those of downhill runners; the

Journal

Journal of Applied PhysiologyThe American Physiological Society

Published: Jan 1, 1983

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