J. A. Oral Roberts University School of Medicine, R. B., fc. W. J. A. . to rat skeletal . J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 54( 1): 8093, 1983.-These experiments were designed to study skeletal pathology resulting from -biased exercise in rats. The effects on the s of running on a treadmill on a O incline (similar amounts of concentric contractions), down a 16â incline (primarily contractions), up a 16â incline (primarily concentric contractions) at 16 me min-l for 90 min were assessed by following postexercise changes in 1) plasma creatine kinase lactate dehydrogenase activities, 2) glucose-6-phosphate dehydrogenase (G-6-PDase) (bio- histochemically) in the physiological extensor s, 3) histological appearance of the s. The data indicate the following. 1) Whereas all exercise protocols resulted in elevations of plasma enzymes immediately after running, only exercise caused late phase elevations 1.5-2 days postexercise. 2) Significant increases in G-6PDase , which were always associated with accumulations of mononuclear cells, always occurred within some s of each extensor group l-3 days following downhill uphill running did not occur following level running; the increases in were usually of lower magnitude in the s of uphill runners than in those of downhill runners; the
Journal of Applied Physiology – The American Physiological Society
Published: Jan 1, 1983
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