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Comparative evaluation of pressure and time factors in estimating left ventricular performance

Comparative evaluation of pressure and time factors in estimating left ventricular performance PHYSIOLOGY Vol. 40, No. 2, February Printed in U.S.A. Comparative in estimating FRANCIS evaluation of pressure and L. ABEL Indiana 46202; Department of Physiology, Indiana University School of Medicine, Indianapolis, and Department of Physiology and Pharmacology, School of Medicine, University of South Carolina, Columbia, South Carolina 29206 ABEL, FRANCIS L. Comparative evahation ofpressure and in estimating . J. Appl. Physiol. 40(Z): 196-205. 1976. - and ascending aortic pressures were measured in open chest mongrel dogs under pentobarbital anesthesia. The data were digitized, averaged, and subgrouped by mean systolic aortic pressures (MSAP), end-diastolic pressure (EDP), and heart rate (HR). Seven raw and 32 derived variables from the pressure, as a function of , wave forms were analyzed in each subgroup in the control state and following the infusion of catecholamines, A plot of control variability versus sensitivity to norepinephrine indicates that to peak pressure (PVP ) is a more sensitive indicator of changes in the inotropic state than such other commonly used variables as max dP/dt, integrated isometric tension, and (max dPl&)/developed pressure. PVP also showed less variability with HR, EDP, and MSAP. Regression lines were also fiit to the data using a second-order model. This permitted evaluation of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Applied Physiology The American Physiological Society

Comparative evaluation of pressure and time factors in estimating left ventricular performance

F. L. Abel
Journal of Applied Physiology , Volume 40: 196 – Feb 1, 1976
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Publisher
The American Physiological Society
Copyright
Copyright © 1976 the American Physiological Society
ISSN
8750-7587
eISSN
1522-1601
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Abstract

PHYSIOLOGY Vol. 40, No. 2, February Printed in U.S.A. Comparative in estimating FRANCIS evaluation of pressure and L. ABEL Indiana 46202; Department of Physiology, Indiana University School of Medicine, Indianapolis, and Department of Physiology and Pharmacology, School of Medicine, University of South Carolina, Columbia, South Carolina 29206 ABEL, FRANCIS L. Comparative evahation ofpressure and in estimating . J. Appl. Physiol. 40(Z): 196-205. 1976. - and ascending aortic pressures were measured in open chest mongrel dogs under pentobarbital anesthesia. The data were digitized, averaged, and subgrouped by mean systolic aortic pressures (MSAP), end-diastolic pressure (EDP), and heart rate (HR). Seven raw and 32 derived variables from the pressure, as a function of , wave forms were analyzed in each subgroup in the control state and following the infusion of catecholamines, A plot of control variability versus sensitivity to norepinephrine indicates that to peak pressure (PVP ) is a more sensitive indicator of changes in the inotropic state than such other commonly used variables as max dP/dt, integrated isometric tension, and (max dPl&)/developed pressure. PVP also showed less variability with HR, EDP, and MSAP. Regression lines were also fiit to the data using a second-order model. This permitted evaluation of

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Journal of Applied Physiology – The American Physiological Society

Published: Feb 1, 1976

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