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Chylomicrons in Diabetics

Chylomicrons in Diabetics N THE COURSE OF OUR WORK the chylomicrs of young of old people (I-4), the problem suggested itself to test diabetic patients, because fat metabolism appears to be timately cnected with sul. The hyperlipemia ketosis of the diabetic are well known. Diabetic patients (5, 6) alloxan diabetic rats (7) derive benefit from a high fat diet, pancreatectomized rats did not show symptoms of diabetes so lg as they were kept a high fat diet (8). With the use of isotopic tracer elements (9, IO), sul appeared to crease fat synthesis rats. alloxan diabetic rats rabbits, synthesis of fats from glucose was less than normal ctrols, this could be reversed with sul (I I, I 2). A relati between diabetes arteriosclerosis is evident, our previous work suggested a relatiship between fat particles the blood arteriosclerosis (2). These csideratis stimulated us to compare serum chylomicr nephelometer curves followg admistrati of stard fat meals ndiabetic diabetic aged . TECHNIQUE The methods for countg chylomicrs serum the use of the nephelometer have been described previously (I, 3, 4) .2 The groups tested comprised 13 normal young, 12 aged ndiabetic, 13 aged diabetic . The had their regular supper the night before nothg http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Applied Physiology The American Physiological Society

Chylomicrons in Diabetics

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Publisher
The American Physiological Society
Copyright
Copyright © 1952 the American Physiological Society
ISSN
8750-7587
eISSN
1522-1601
Publisher site
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Abstract

N THE COURSE OF OUR WORK the chylomicrs of young of old people (I-4), the problem suggested itself to test diabetic patients, because fat metabolism appears to be timately cnected with sul. The hyperlipemia ketosis of the diabetic are well known. Diabetic patients (5, 6) alloxan diabetic rats (7) derive benefit from a high fat diet, pancreatectomized rats did not show symptoms of diabetes so lg as they were kept a high fat diet (8). With the use of isotopic tracer elements (9, IO), sul appeared to crease fat synthesis rats. alloxan diabetic rats rabbits, synthesis of fats from glucose was less than normal ctrols, this could be reversed with sul (I I, I 2). A relati between diabetes arteriosclerosis is evident, our previous work suggested a relatiship between fat particles the blood arteriosclerosis (2). These csideratis stimulated us to compare serum chylomicr nephelometer curves followg admistrati of stard fat meals ndiabetic diabetic aged . TECHNIQUE The methods for countg chylomicrs serum the use of the nephelometer have been described previously (I, 3, 4) .2 The groups tested comprised 13 normal young, 12 aged ndiabetic, 13 aged diabetic . The had their regular supper the night before nothg

Journal

Journal of Applied Physiology – The American Physiological Society

Published: May 1, 1952

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