, M., C. GAUTHIER, K. EL TAYEB,G. HETENYIJR., glucoregulatory . We have studied in normal dogs, the effects of a) hypoglycemia: mild to cholamine responses and their moderate, phlorizin infusion; severe, infusion; b) g&tory . Am. J. Physiol. 247 (Endocrinol. Metab. exercise; c) P-endorphin infusion. 10): El45-E156, 1984.-We have investigated We have also used epinephrine infusions to further glucagon- using three stressmodels:1) hydelineate the metabolic effects of epinephrine and interpoglycemia; 2) exercise;and 3) epinephrine infusion, Phlorizin causedmild hypoglycemia hypoemia. Plasma glu- actions between epinephrine and the counterregucagon increased as did hepatic production. Catechol- latory . Studies have been carried out in a) dogs; c) depancreatized amines did not increase. causedsevere hypoglycemia. normal dogs; b) alloxan-diabetic Metabolic counterregulation was due mainly to the 40-fold dogs i) in good metabolic control and ii) in poor metabolic increase in epinephrine. Glucagon played a role only in the control. D. BILINSKI, D. WASSERMAN, AND H. L. A. LICKLEY. Cate glucore- recovery from -induced hypoglycemia, which could reflect increased hepatic sensitivity to glucagon declining plasma . Glucagon suppressionduring exercise caused transient hypoglycemia due to an inadequate rise in production. Exaggerated epinephrine releaseduring hypoglycemic exercise prevented severe hypoglycemia by inhibiting utilization and stimulating production,
AJP - Endocrinology and Metabolism – The American Physiological Society
Published: Aug 1, 1984
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