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Physiology, and Biophysics, University of Washington, T. Bioelectrical and contractile behavior of superius: estrogen withdrawal. Am. J. Physiol. 233(5): C180-(X87,1977 or Am. J. Physiol.: Cell Physiol. 2(3): CM-C187, 1977. -The mesotubarium superius of the female is a thin, plane sheet of responding to the in vivo endocrine states of ovulation, estrous, castration, pregnancy, and replacement estrogen therapy of the castrate in a manner similar to that of the uterus. Both isometric tension and microelectrode recorded transmembrane potentials were measured in vitro to make these comparisons. In addition, confirmation of the âestrogen-withdrawalâ theory of activation was obtained when it was noted that about 12 h after an abrupt withdrawal of estrogen there is an increase in contractile activity coinciding with an increase in subthreshold activity and a slight (about 5 mV> decline in the average resting potential compared to the control estrous level. It is concluded that the mesotubarium superius is an excellent tissue for reproductive studies, where a geometrically simple model is useful. CONRAD, mesotubarium One of the problems in combining these two disparate disciplines has been the difficulty in finding and using a simple system for investigational purposes. There is a need in reproductive investigation for an
AJP - Cell Physiology – The American Physiological Society
Published: Nov 1, 1977
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