THOMAS J. MANFREDI, WENJING DING, WILLIAM J. EVANS, AND JOSEPH G. CANNON Human Physiology L&oratory, United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, and Department of Medicine, New England Medical Center and Tufts University School of Medicine, Boston, Massachusetts 02111; and Applied Physiology L&oratory, Department of Physical Education, University of Rhode Island, Kingston, Rhode Island 02881 Fielding, Ding, Maria G. Cannon. Roger A., Thomas J. Manfredi, A. Fiatarone, William J. Evans, Integrative Camp. Physiol. Wenjing and Joseph 1993. and IL-lb (Regulatory Acute phaseresponse .III. Neutrophil in accumulation in skeletal.Am. J. Phyd. 265 34): Rl66-R172, -Nine untrained men (22-29 yr) performed 45 min of downhill running (16% incline, 70% of maximum heart rate). Needle biopsiesof the vastus lateralis were performed before, 45 min , and 5 days .Immunohistochemicalstaining of cross sections revealed a 135% increase in interleukin-l@ (IL-l/3) immediately and a 250% increase (P < 0.03) 5 days .Using a rating scale (O-3) for the presence of , light microscopic examination showeda significant accumulation of in biopsiestaken 45 min and 5 days [before: 0.5 & 0.2,45 min : 1.5 & 0.3 (P < O.Ol), and 5 days : 1.2 t 0.2 (P < 0.04)].
AJP - Regulatory, Integrative and Comparative Physiology – The American Physiological Society
Published: Jul 1, 1993
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