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Accurate determination of O2 dissociation curve of human blood above 98.7 percent saturation with data on O2 solubility in unmodified human blood from 0 degrees to 37 degrees C

Accurate determination of O2 dissociation curve of human blood above 98.7 percent saturation with... in U.S.A. Accurate human solubility determination blood in unmodified of 0, dissociation 98.7yo uration blood with from human data of on 0, 0” to 37O C J. W. VERIKGHAUS Department of Colloid Science, Cambridge University, Cambridge, Engl; Cardiovascular Rearch h&jute, University of Culifurnia Medical Center, Sun Fran&u, California F. J, W., J+ IV. VERINGHAUS. Accurate deterof 0 2 dissociation curw of human blood 98.7% uration with data on 02 solubiliiy in unmodified human blood from O0 to 37O C. J. Appl. Physiol. 35(6) : 861-869. 1973.-The position of the normal human blood oxygen dissociation between 98.7 y0 99.6(% S (0 2 uration) was determined to an accuracy of &O. 1 :‘/i SD with 37 samples of blood from four normal nonsmoking males by u of a new technique. Deuration was determined by measuring Peg in electrodes at 37’ 0’ C. At S > 98.77& 02 affinity of hemoglobin increas 22-fold on cooling from 37” to O” C, sufficient dissolved oxygen is prent at 37” to fully urate the hemoglobin upon cooling. PO 2 measurement at 37’ //or 0 O, combined with anaerobic mixing of urated deurated blood samples, was also ud to obtain the following computing correctional factors: http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Applied Physiology The American Physiological Society

Accurate determination of O2 dissociation curve of human blood above 98.7 percent saturation with data on O2 solubility in unmodified human blood from 0 degrees to 37 degrees C

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Publisher
The American Physiological Society
Copyright
Copyright © 1973 the American Physiological Society
ISSN
8750-7587
eISSN
1522-1601
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Abstract

in U.S.A. Accurate human solubility determination blood in unmodified of 0, dissociation 98.7yo uration blood with from human data of on 0, 0” to 37O C J. W. VERIKGHAUS Department of Colloid Science, Cambridge University, Cambridge, Engl; Cardiovascular Rearch h&jute, University of Culifurnia Medical Center, Sun Fran&u, California F. J, W., J+ IV. VERINGHAUS. Accurate deterof 0 2 dissociation curw of human blood 98.7% uration with data on 02 solubiliiy in unmodified human blood from O0 to 37O C. J. Appl. Physiol. 35(6) : 861-869. 1973.-The position of the normal human blood oxygen dissociation between 98.7 y0 99.6(% S (0 2 uration) was determined to an accuracy of &O. 1 :‘/i SD with 37 samples of blood from four normal nonsmoking males by u of a new technique. Deuration was determined by measuring Peg in electrodes at 37’ 0’ C. At S > 98.77& 02 affinity of hemoglobin increas 22-fold on cooling from 37” to O” C, sufficient dissolved oxygen is prent at 37” to fully urate the hemoglobin upon cooling. PO 2 measurement at 37’ //or 0 O, combined with anaerobic mixing of urated deurated blood samples, was also ud to obtain the following computing correctional factors:

Journal

Journal of Applied Physiology – The American Physiological Society

Published: Dec 1, 1973

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